A pharmacoeconomic evaluation of capsofungin and amphotericin B for intravenous infusion for treatment of systemic fungal infection

Zivkovic, Marija; Lakic, Dragana; Tadić, Ivana; Odalović, Marina; Bogavac-Stanojević, Nataša

doi:10.5937/arhfarm1501033z

Arh farmaciju

2015

DOI: 10.5937/arhfarm1501033z

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A pharmacoeconomic evaluation of capsofungin and amphotericin B for intravenous infusion for treatment of systemic fungal infection

Marija Zivkovic¹,

Dragana Lakic²,

Ivana Tadić³

et al.

Abstract: Empirijska primena antimikotika u terapiji invazivnih gljivičnih infekcija (IGI) u febrilnoj neutropeniji predstavlja značajan trošak, ali je neophodna kod pacijenata sa leukemijom i nakon transplantacije matičnih ćelija hematopoeze. Brojne kliničke studije pokazale su male razlike u efikasnosti amfotericina B i kaspofungina u empirijskoj terapiji IGI, ali to ne oslikava u pravoj meri odnos trošak-efektivnost. Cilj rada je bio poređenje isplativosti kaspofungina i amfotericina B lipidni kompleks (ABLC) u empir… Show more

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2021

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Modelling in economic evaluations of medicines

Lakic¹,

Stević²,

Odalović³

et al. 2021

Arhiv za farmaciju

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Economic evaluation in health (also known as pharmacoeconomic in case of medicines) identifies, measures, and values costs and outcomes of alternative healthcare technologies, and can be performed alongside controlled clinical trials, but analytical modelling is usually used. Decision trees and Markov models are the two most common approaches used in economic evaluation. The biggest advantages of a decision tree are clarity, simplicity, and straightforwardness. On the other hand, the main advantage of the Markov model is its ability to incorporate complex events into the simulation, which is practically impossible to do with a decision tree. Reimbursement policy in Serbia mandatorily incorporates economic evaluations to promote availability and accessibility of the prescription medicines. To show current pharmacoeconomic value of a medicine, budget impact analysis and the cost-effectiveness analysis should be included. The latter should be conducted using appropriate modelling techniques. However, since no official methodological guidelines about the modelling and economic analysis exist, the submissions by marketing authorization holders vary greatly. The future of pharmacoeconomic modelling depends on the research area of interest, with new frameworks and approaches being developed.

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Modelling in economic evaluations of medicines

Lakic¹,

Stević²,

Odalović³

et al. 2021

Arhiv za farmaciju

View full text Add to dashboard Cite

show abstract

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A pharmacoeconomic evaluation of capsofungin and amphotericin B for intravenous infusion for treatment of systemic fungal infection

Cited by 1 publication

References 5 publications

Modelling in economic evaluations of medicines

Modelling in economic evaluations of medicines

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