A Pharmacological Approach to Allergy

West, G. B.

doi:10.1007/978-3-0348-7041-2_5

Cited by 3 publications

(1 citation statement)

References 185 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Wells (1962) reported increased numbers of tissue eosinophils in the intestines of rats 12 days after infection with Nippostrongylus brusiliensis which she interpreted as being related to the low tissue histamine levels and decreased numbers of mast cells also noted in the intestine. Cellular mechanisms in nematode-induced allergic reactions may coincide with that proposed for other systems (West, 1961;Mongar and Schild, 1962;Mota, 1963), although experimental data for nematode systems are at present very inadequate.…”

Section: Discussionmentioning

confidence: 86%

NEMATODE INDUCED HYPERSENSITIVITY REACTIONS IN GUINEA PIGS: ONSET OF EOSINOPHILIA AND POSITIVE SCHULTZ‐DALE REACTIONS FOLLOWING GRADED INFECTIONS WITH TOXOCARA CANIS

Olson

Schulz

1963

Annals of the New York Academy of Sciences

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 86%

NEMATODE INDUCED HYPERSENSITIVITY REACTIONS IN GUINEA PIGS: ONSET OF EOSINOPHILIA AND POSITIVE SCHULTZ‐DALE REACTIONS FOLLOWING GRADED INFECTIONS WITH TOXOCARA CANIS

Olson

Schulz

1963

Annals of the New York Academy of Sciences

View full text Add to dashboard Cite

Insulin-induced factors derived from lymph node cells influence anaphylactoid reaction in the rat

1983

View full text Add to dashboard Cite

The effect of supernatants of isolated lymph node cells exposed to insulin has been studied on the anaphylactoid reaction induced by dextran in the rat paw. Native supernatants derived from rat lymphocytes were shown to increase dextran response only from April to October, while in the intermediate period no potentiation was obtained. The supernatants were filtered through sephadex G-25, G-50, and G-100 gels. Pro-inflammatory activity was recovered in the void volume of sephadex G-25 or G-50 columns, while it ran with bovine serum albumin marker suggesting an approximate mol. wt. of 70-kilodalton. Potentiation was detectable in adrenalectomized rats from November through April. A fraction of the eluate recovered from sephadex G-25 gels in the range of 1- to 6-kilodalton was found to suppress dextran edema. Supernatants of calf lymph node cells with insulin were fractionated on DEAE-sephadex A-50 and yielded two distinct fractions, one with pro-inflammatory and the other with anti-inflammatory effect. These results suggest that insulin affects anaphylactoid reaction via the release of some lymphocyte mediators.

show abstract

Current Concepts of the Pathogenesis of the So-Called Collagen Diseases

Venters¹,

Good²

1963

Pediatric Clinics of North America

View full text Add to dashboard Cite

A Pharmacological Approach to Allergy

Cited by 3 publications

References 185 publications

NEMATODE INDUCED HYPERSENSITIVITY REACTIONS IN GUINEA PIGS: ONSET OF EOSINOPHILIA AND POSITIVE SCHULTZ‐DALE REACTIONS FOLLOWING GRADED INFECTIONS WITH TOXOCARA CANIS

NEMATODE INDUCED HYPERSENSITIVITY REACTIONS IN GUINEA PIGS: ONSET OF EOSINOPHILIA AND POSITIVE SCHULTZ‐DALE REACTIONS FOLLOWING GRADED INFECTIONS WITH TOXOCARA CANIS

Insulin-induced factors derived from lymph node cells influence anaphylactoid reaction in the rat

Current Concepts of the Pathogenesis of the So-Called Collagen Diseases

Contact Info

Product

Resources

About