A Pharmacological Study of a Homologous Series of Sodium Alkyl Sulfates†

Gale, Laurence E.; Scott, Paul M.

doi:10.1002/jps.3030420504

Cited by 15 publications

(1 citation statement)

References 5 publications

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“…The IP LD 50 of sodium ethylhexyl sulfate was determined using groups of 10 mice, 5 per sex per group. 18 The IP LD 50 for mice was 396 mg/kg. No further details were provided.…”

Section: Acute Parenteral Toxicitymentioning

confidence: 99%

Final Report on the Safety Assessment of Sodium Cetearyl Sulfate and Related Alkyl Sulfates as Used in Cosmetics

Fiume¹,

Bergfeld

Belsito

et al. 2010

Int J Toxicol

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Sodium cetearyl sulfate is the sodium salt of a mixture of cetyl and stearyl sulfate. The other ingredients in this safety assessment are also alkyl salts, including ammonium coco-sulfate, ammonium myristyl sulfate, magnesium coco-sulfate, sodium cetyl sulfate, sodium coco/hydrogenated tallow sulfate, sodium coco-sulfate, sodium decyl sulfate, sodium ethylhexyl sulfate, sodium myristyl sulfate, sodium oleyl sulfate, sodium stearyl sulfate, sodium tallow sulfate, sodium tridecyl sulfate, and zinc coco-sulfate. These ingredients are surfactants used at concentrations from 0.1% to 29%, primarily in soaps and shampoos. Many of these ingredients are not in current use. The Cosmetic Ingredient Review (CIR) Expert Panel previously completed a safety assessment of sodium and ammonium lauryl sulfate. The data available for sodium lauryl sulfate and ammonium lauryl sulfate provide sufficient basis for concluding that sodium cetearyl sulfate and related alkyl sulfates are safe in the practices of use and concentration described in the safety assessment.

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“…The IP LD 50 of sodium ethylhexyl sulfate was determined using groups of 10 mice, 5 per sex per group. 18 The IP LD 50 for mice was 396 mg/kg. No further details were provided.…”

Section: Acute Parenteral Toxicitymentioning

confidence: 99%