“…Evidence of a synergistic interaction between these treatment types remains lacking. Survival updates for phase 2 trials using nivolumab, ipilimumab, and Trabectedin for previously untreated advanced STS were reported in this year’s ASCO meeting, with an ORR of 26.6% 19 . Another combination of PD-1 inhibitor retifanlimab with chemotherapy with gemcitabine and docetaxel as first-line therapy in a phase I/II study was associated with a maximum ORR of 50% and a DCR of 100% 20 .…”