2012
DOI: 10.1089/neu.2011.1895
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A Phase I Study of Low-Pressure Hyperbaric Oxygen Therapy for Blast-Induced Post-Concussion Syndrome and Post-Traumatic Stress Disorder

Abstract: This is a preliminary report on the safety and efficacy of 1.5 ATA hyperbaric oxygen therapy (HBOT) in military subjects with chronic blast-induced mild to moderate traumatic brain injury (TBI)/post-concussion syndrome (PCS) and post-traumatic stress disorder (PTSD). Sixteen military subjects received 40 1.5 ATA/60 min HBOT sessions in 30 days. Symptoms, physical and neurological exams, SPECT brain imaging, and neuropsychological and psychological testing were completed before and within 1 week after treatment… Show more

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Cited by 137 publications
(139 citation statements)
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“…There have been investigations of HBO 2 therapy for blast-induced postconcussion syndrome and posttraumatic stress disorder. 22 The patients experienced their injuries at least 12 months prior to HBO 2 treatment. The preliminary report by Harch et al 22 suggests that HBO 2 should be studied in a larger catchment of patients.…”
Section: Blast Injuries and Hbomentioning
confidence: 99%
See 1 more Smart Citation
“…There have been investigations of HBO 2 therapy for blast-induced postconcussion syndrome and posttraumatic stress disorder. 22 The patients experienced their injuries at least 12 months prior to HBO 2 treatment. The preliminary report by Harch et al 22 suggests that HBO 2 should be studied in a larger catchment of patients.…”
Section: Blast Injuries and Hbomentioning
confidence: 99%
“…22 The patients experienced their injuries at least 12 months prior to HBO 2 treatment. The preliminary report by Harch et al 22 suggests that HBO 2 should be studied in a larger catchment of patients. The mechanism of action of HBO 2 in this setting has not been clearly delineated.…”
Section: Blast Injuries and Hbomentioning
confidence: 99%
“…PCS is a well-studied entity across many populations after general trauma, military blast injury, and SRC. 25,39,67,69 Tator et al 69 comprehensively described the phenotype of PCS across 138 athletes, where most patients were younger than 30 years with an average of 7.6 symptoms for a median of 6 months. As both populations have symptom duration of weeks to months, differentiating between a recovering PCS patient with no structural injury versus one with an AC associated SDH or hygroma becomes challenging.…”
Section: Presentationmentioning
confidence: 99%
“…However, recent scientific studies published in the Journal of Neurotrauma [14] and by the Sackler School of Medicine of Tel Aviv University [15] report that TBI subjects with posttable 2.…”
Section: Treating the Injured Brainmentioning
confidence: 99%