Seven different chemical kinetic mechanisms for n-dodecane, two detailed and five reduced, have been evaluated under Engine Combustion Network (ECN) thermodynamic conditions by comparison to experimental measurements in a Rapid Compression-Expansion Machine (RCEM). The target ECN conditions are imposed at Top Dead Center (TDC), which cover a wide range of temperatures (from 850 K to 1000 K), oxygen molar fractions (0.