Infertility affects millions of women worldwide and can lead to increased levels of stress and anxiety, impacting overall well-being and quality of life. Relaxation techniques, such as Mindfulness-Based Stress Reduction (MBSR), Yoga, Progressive Muscle Relaxation Technique (PMR), and Guided Imagery, have emerged as potential interventions to alleviate emotional distress in infertile women. A comprehensive review of the existing literature is needed to assess the effectiveness of these techniques in addressing stress and anxiety in the context of infertility.Following PRISMA guidelines, a systematic review was conducted by searching electronic databases for relevant studies published up to September 2021. The search used keywords related to relaxation techniques, infertility, stress, and anxiety. Two reviewers screened the identified articles based on predefined criteria. Included studies examined the effectiveness of relaxation techniques in reducing stress and anxiety among infertile women and used validated measures as outcomes. Data extraction and quality assessment were independently performed.The review included 18 studies that explored various relaxation techniques' effectiveness in reducing stress and anxiety among infertile women. MBSR, Yoga, PMR, and Guided Imagery interventions consistently showed significant reductions in perceived stress and anxiety levels. MBSR interventions proved particularly promising in promoting emotional well-being and coping with infertility challenges. Yoga offered a holistic approach, incorporating physical postures, breath control, and meditation to address multifaceted stress. PMR provided practical coping tools, and Guided Imagery offered guided visualization for anxiety management.This systematic review highlights the potential of relaxation techniques like MBSR, Yoga, PMR, and Guided Imagery in reducing stress and anxiety among infertile women. These interventions offer accessible and cost-effective strategies to enhance emotional well-being and coping skills in infertility contexts. Healthcare providers and counselors can consider incorporating these techniques into treatment plans to address the emotional needs of infertile women and improve their overall well-being and quality of life.