A photocrosslinked methacrylated carboxymethyl chitosan/oxidized locust bean gum double network hydrogel for cartilage repair

Abstract

Repairing articular cartilage defects is a great challenge due to the poor self-regenerative capability of cartilage. Inspired by natural cartilage extracellular matrix active substances, we use methacrylated carboxymethyl chitosan (MA-CMCS)...

Near-infrared light-actuated on-demand botanicals release and hyperthermia by an antibiotic-free polysaccharide-based hydrogel dressing for the synergistic treatment of wound infections

“…Among the many available wound dressings, hydrogel dressings can improve the wound environment, resist infection, and promote wound healing, 25 which has attracted great attention in tissue repair. 26 The hydrogels are a class of threedimensional network dressings with chemical or physical cross-linking structure, 27,28 which can provide a moist environment for skin cells, promote oxygen exchange and water molecule penetration, and prevent the invasion of microorganisms such as bacteria. [29][30][31] Therefore, the selection of suitable materials for the preparation of hydrogels has become an effective strategy for combating wound infections.…”