A physiological control system for ECG-synchronized pulsatile pediatric ventricular assist devices

Cordeiro, Thiago; Sousa, Daniel L.; Cestari, Idágene Aparecida; Lima, A.M.N.

doi:10.1016/j.bspc.2019.101752

Cited by 10 publications

(7 citation statements)

References 29 publications

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“…o qual gera a seguinte equação de diferenças para o cálculo da saída do controlador: O método de sintonia escolhido para este trabalho foi adaptado de [12], ou seja, utilizando o método de Nelder-Mead para um problema de minimização restrita [15]. Porém, adicionou-se ao processo de otimização a variável λ, referente ao atraso temporal entre δ QRS e δ PDAV .…”

Section: Projeto Do Controlador S íNcronounclassified

“…Assim, a formulação geral do problema de encontrar um vetor ótimo θ * , adaptando a metodologia descrita em [12], é dada por:…”

Section: Projeto Do Controlador S íNcronounclassified

“…Em outro trabalho desenvolvido pelo mesmo autor [12], modelos pediátricos do SCH e do PDAV também foram utilizados para avaliar o desempenho de controladores polinomiais discretos de diferentes ordens. Os parâmetros das funções de transferência destes controladores foram sintonizados utilizando-se um método de otimização para minimizar o erro entre variáveis hemodinâmicas para variações do tipo degrau.…”

Section: Introdu ç ãOunclassified

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Investigando a importância do instante de ejeção de dispositivos de assistência ventricular pulsáteis para o desempenho de controladores síncronos

Santos

Patriota

Matos

et al. 2021

Procedings Do XV Simpósio Brasileiro De Automação Inteligente

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Cardiovascular diseases represent a large portion of the main cause of death in Brazil. In severe cardiovascular dysfunctions, a good treatment is using mechanical pumps called ventricular assist devices (VADs), which are designed to extend the patient's life perspective. This work proposes to use computer simulation for modeling a VAD coupled to an adult human cardiovascular system model, under the influence of a control system that changes the ejection instant, designed to improve the physiological response of patients. As a starting point, techniques available in the literature, which have fixed parameters, were analyzed under changing the values of these parameters. Performance indexes based on the error signal were used to compare the original techniques and after modifications. Finally, the computational simulation results were analyzed the discovered solutions, finding the ideal parameters from the minimization of the error signal. Resumo: As doenças cardiovasculares representam grande parte das principais causas de morte no Brasil. Em disfunções cardiovasculares graves, um bom tratamento é o uso de bombas mecânicas chamadas dispositivos de assistência ventricular (DAVs), que são projetadas para estender a perspectiva de vida do paciente. Este trabalho propõe o uso de simulação computacional para modelagem de um DAV acoplado a um modelo de sistema cardiovascular humano adulto, sob a influência de um sistema de controle que altera o instante de ejeção, projetado para melhorar a resposta fisiológica dos pacientes. Como ponto de partida, técnicas disponíveis na literatura, e que operam com parâmetros fixos, foram analisadas com a alteração dos valores desses parâmetros. Índices de desempenho baseados no sinal de erro foram usados para comparar as técnicas originais e após as modificações. Por fim, os resultados da simulação computacional foram analisados das soluções descobertas, encontrando os parâmetros ideais a partir da minimização do sinal de erro.

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Section: Projeto Do Controlador S íNcronounclassified

“…Assim, a formulação geral do problema de encontrar um vetor ótimo θ * , adaptando a metodologia descrita em [12], é dada por:…”

Section: Projeto Do Controlador S íNcronounclassified

Section: Introdu ç ãOunclassified

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Investigando a importância do instante de ejeção de dispositivos de assistência ventricular pulsáteis para o desempenho de controladores síncronos

Santos

Patriota

Matos

et al. 2021

Procedings Do XV Simpósio Brasileiro De Automação Inteligente

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“…To meet the perfusion prerequisites for different physiological states of the patient, a variable speed physiological control system is needed for adjusting the motor speed. The Frank-Starling mechanism that mimics the natural heart has been used widely in the development of variable speed physiological control systems [5][6][7][8][9]. Stevens MC et al proposed a control strategy mimicking the Frank-Starling mechanism by directly measuring LAP with a pressure sensor and mounting a flow sensor at the pump outlet catheter used to measure pump flow [5].…”

Section: Introductionmentioning

confidence: 99%

“…Petrou et al proposed a physiological controller based on left ventricular systolic pressure [6]. Cordeiroa put forward a synchronous physiological control system of a pulsatile pediatric pump to adjust the pump ejection pressure at each cardiac cycle to keep the mean arterial pressure at a specified reference value [7]. Fetanat developed a novel adaptive physiological control system for an implantable heart pump to respond to interpatient and intra-patient variations to maintain the left ventricular end-diastolic pressure in the normal range to prevent ventricle suction and pulmonary congestion.…”

Section: Introductionmentioning

confidence: 99%

A Non-Invasive Physiological Control System of a Rotary Blood Pump Based on Preload Sensitivity: Use of Frank–Starling-Like Mechanism

Wang

et al. 2022

Micromachines

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Implanting rotary blood pumps (RBPs) has become the principal treatment for patients suffering from severe heart failure. There are still many challenges to address for RBP control systems. These problems include meeting the patient’s physiological perfusion, eliminating postoperative complications, as well as debugging the patient’s physiological control system (automatically and indiscriminately). This paper proposes a non-invasive adaptive control system based on the Frank–Starling-like mechanism (NAC-FSL) to solve these problems. This control system uses the motor speed of the rotary blood pump as the only input variable, and the pump flow was estimated by the motor speed for achieving non-invasive detection. Simultaneously, a cardiovascular reference model was developed to provide an appropriate real-time preload for heart failure patients. The Frank–Starling-like control baseline was tracked to obtain the desired reference average pump flow by using the preload. Avoiding suction was done by adopting the control baseline (CLn), which included a flat slope under a high preload. Moreover, the NAC-FSL system could potentially unload the left ventricle and provide a higher pump flow with a smaller error during the exercise state, as compared to the CSC system. Finally, the K value indicating the preload sensitivity in the NAC-FSL controller was optimized to meet the perfusion needs according to the hemodynamic parameters.

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Physiological Control of Pulsatile and Rotary Pediatric Ventricular Assist Devices

Melo

Cordeiro

Cestari³

et al. 2022

XXVII Brazilian Congress on Biomedical Engineering

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A physiological control system for ECG-synchronized pulsatile pediatric ventricular assist devices

Cited by 10 publications

References 29 publications

Investigando a importância do instante de ejeção de dispositivos de assistência ventricular pulsáteis para o desempenho de controladores síncronos

Investigando a importância do instante de ejeção de dispositivos de assistência ventricular pulsáteis para o desempenho de controladores síncronos

A Non-Invasive Physiological Control System of a Rotary Blood Pump Based on Preload Sensitivity: Use of Frank–Starling-Like Mechanism

Physiological Control of Pulsatile and Rotary Pediatric Ventricular Assist Devices

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