A Phytochemical and Ethnopharmacological Recapitulation on Hamelia patens

Abstract

The world health organization reports that 80% of the population living within the developing countries depends basically on traditional medicine for his or her primary health care. Quite half the entire world's population still depends entirely on plants for medicines, and plants provides the active ingredients to the most traditional medical products. Hamelia patens that belong to the family Rubiaceae, is mainly found in tropical and sub-tropical areas. It is used in folk medicine against a wide range of diseases such as athlete’s foot, skin problems, insect sting, psychiatric disorder, rheumatism, headache, asthma, dysentery, menses, ovarian and uterine disorders. Hamelia consists of an important bioactive constituent such as oxindole alkaloids, flavonoids, and phenolic content. Due to the presence of chlorogenic acid and epicatechin constituent in the methanolic extract of Hamelia patens, there is a noticeable anti-hyperglycemic activity as well as it possesses antioxidant activity. Acute and sub-acute toxicity study has been performed on Hamelia patens which shows that it is safe and can be used for humans. Against fungi and bacteria, the ethanol leaf extract of Hamelia has a maximum inhibitory effect. The plant has various therapeutic effects like anti-inflammatory, analgesic, anti-diarrheal, anthelmintic, antidepressant, hepatoprotective, antiurolithiatic, diuretic, wound healing, and many others. In this article, we have discussed chemical constituent, pharmacological activity and traditional use of Hamelia patens.

The Ultrasound-Assisted Extraction of Polyphenols from Mexican Firecracker (Hamelia patens Jacq.): Evaluation of Bioactivities and Identification of Phytochemicals by HPLC-ESI-MS

“…In the purified phytochemicals fraction of H. patens, the chemical groups of alkaloids, sterols, flavonoids, coumarins, and phenolic hydroxyls were identified. These results are largely in agreement with those reported by Noor et al [4] and Rubio Fontanills et al [5], who report the presence of alkaloids, tannins, glycosides, saponins, steroids, flavonoids, terpenoids, and coumarins in ethanolic extract.…”

“…Hamelia patens Jacq. (Rubiaceae) has been reported to possess compounds with important bioactivities, because it has been used in traditional Mexican medicine [3][4][5]. It has been reported to possess several bioactivities in vitro and in vivo, including antihemorrhagic [6], hepatoprotective, antioxidant [7], antihyperglycemic [8], and antibacterial [5] properties, among others.…”

Unlocking the food treasures:Trachyspermum ammi–A comprehensive exploration from field to pharmacology

“…Currently, there is a heightened interest in utilizing natural antibacterial compounds, such as essential oils and extracts from various edible and medicinal plants and herbs. These have traditionally been employed for food preservation purposes, owing to their antimicrobial properties (Ansari et al., 2021; Noor et al., 2020). The main aim of this review is to provide a detailed summary covering the medicinal attributes, pharmacological importance, traditional applications, and recent progress in the research on T. ammi .…”