“…Univariate associations were reported for the presence of cardiopulmonary disease 14 and diabetes mellitus, 18,19 whereas multivariate associations were reported for age, 26 chronic obstructive pulmonary disease (COPD), 20 protein calorie malnutrition, 20 and ambulatory assist devices. 20 There were six disease factors associated with postinjury morbidity examined across included studies. Univariate associations were reported for the need for early mechanical ventilation, 15 oxygen saturation, 18 and number of rib fractures, 18,19 whereas multivariate associations were reported for the need of tube thoracostomy, 20 increasing ISS, 20 per one increase in number of ribs fractured, 20 or having eight or more ribs fractured.…”