2024
DOI: 10.4078/jrd.2024.0032
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A pilot study of skin barrier function in patients with systemic sclerosis and primary Sjögren’s syndrome

Kyung-Ann Lee,
Sooyoung Kim,
Ho-Yeon Song
et al.

Abstract: Although the close interactions between the epidermis and dermis of the skin have been widely explored, the skin barrier functions of the stratum corneum (SC) in patients with systemic sclerosis (SSc) and primary Sjögren's syndrome (pSS) are not well known. We aimed to investigate the biophysical characteristics of the skin, including transepidermal water loss (TEWL), the SC water content, erythema, and the melanin index, in patients with SSc and pSS. Methods: This case-control study included 34 patients with … Show more

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