The recent proliferation of information technology designed to support or enhance an individual professional's task performance has made the investigation of technology acceptance increasingly challenging and significant. This study investigates technology acceptance by individual professionals by examining physicians' decisions to accept telemedicine technology. Synthesized from relevant prior research, a generic research framework was built to provide a necessary foundation upon which a research model for telemedicine technology acceptance by physicians could be developed. The research model was then empirically examined, using data collected from more than 400 physicians practicing in public tertiary hospitals in Hong Kong. Results of the study suggest several areas where individual "professionals" might subtly differ in their technology acceptance decision-making, as compared with end users and business managers in ordinary business settings. Specifically, physicians appeared to be fairly pragmatic, largely anchoring their acceptance decisions in the usefulness of the technology rather than in its ease of use. When making decisions to Downloaded by [University of Sussex Library] at 10:47 06 February 2015 192 CHAU AND HU accept a technology, physicians expressed considerable concerns about the compatibility of the technology with their practices, placed less importance on controlling technology operations, and attached limited weight to peers' opinions about using the technology. Based on results obtained from this study, the initially proposed framework for technology acceptance by individual professionals was revised to a "hierarchical, three-layer" structure with the individual context at the inner core, the implementation context on the outermost layer, and the technological context residing in the middle. Implications for information systems research and telemedicine management practice that have emerged from the study's findings are also discussed.KEY WORDS AND PHRASES: acceptance of information technology, adoption of information technology, professional users, telemedicine technology management. THE USE OF INFORMATION TECHNOLOGY (IT) has expanded into many areas that can be broadly categorized by applications and target users. Driven by service improvement, market competitiveness enhancement, or bottom-line survival, business organizations have invested heavily in IT and are likely to continue doing so in the near future. Examples of prevalent or highly publicized IT applications for business include technology-enabled process reengineering, open systems, electronic data interchange, and more recently, Internet-based electronic commerce. In the meantime, various IT applications designed to support or enhance individual task performance and services within for-profit and not-for-profit professional organizations have also proliferated rapidly. This phenomenon-the fast-growing acquisition and implementation of innovative IT applications for individual professionals 1 -has demanded effective technology ma...