A pilot trial of large versus small diameter needles for oocyte retrieval

Kushnir, Vitaly A.; Kim, Ann; Gleicher, Norbert; Barad, David H.

doi:10.1186/1477-7827-11-22

Cited by 6 publications

(1 citation statement)

References 12 publications

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“…Reducing the thickness of the needle from 15 gauge to 17 or 18 gauge has previously been shown to reduce pain, without affecting the number of oocytes collected, their quality, or clinical pregnancy rates [4][5][6]. Recently, a prospective pilot study on further miniaturization was conducted, and while a 20-gauge needle did not affect the oocyte yield compared to a 17-gauge needle, it did prolong the procedure time [7]. However, thin needles bend more easily, which can cause the needle tip to shift out of the puncture guide.…”

Section: Introductionmentioning

confidence: 99%

Comparison of a Reduced Needle With a Thin Tip and a Standard Thin Needle (Same Width Overall) for Oocyte Retrieval

Nakabayashi,

Hashimoto,

Horibe

et al. 2024

Cureus

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Introduction: At our facility, oocyte retrieval had previously been performed with a 20-gauge standard needle that is uniformly thin overall (tSN); but recently, we have instead started using reduced needles, with a 20-gauge tip and 17-gauge body (RN). Until now, there have been comparisons between RN and thick standard needles, but there have been no comparisons between RN and tSN. The purpose of this study was to compare oocyte retrieval outcomes using RN with tSN. Methodology: Information on oocyte retrieval was extracted from the medical records of 304 cycles performed at our facility from January 2020 to December 2023. The oocyte retrieval outcomes of the two types of needles were compared retrospectively with respect to age, anti-Müllerian hormone (AMH), procedure time, additional sedatives, number of follicles punctured, number of oocytes retrieved, number of oocytes fertilized, oocyte recovery rate, and fertilization rate. Results: When AMH ≥ 1.2 ng/mL, the procedure time was 9.3 ± 3.7 and 12.1 ± 4.6 minutes in the RN and tSN groups, respectively ( P < 0.001), and the need for additional sedatives was also significantly different: 54.0% in the RN group and 78.5% in the tSN group ( P = 0.002). The oocyte recovery rate was significantly different between the RN and tSN groups at 65.3% and 61.2%, respectively ( P = 0.046), and the fertilization rate was significantly different between the RN and tSN groups at 56.8% and 66.8%, respectively ( P < 0.001). There were no significant differences by age, AMH, number of follicles punctured, number of oocytes retrieved, or number of oocytes fertilized. Conclusions: Without diminished ovarian reserve, RN reduced procedure time and the need for additional sedatives compared to tSN. In addition, the number of oocytes fertilized per oocyte retrieval remained the same, indicating that oocyte retrieval performance was not affected.

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