A Placebo-Controlled Trial of UV-A Phototherapy for the Treatment of Uraemic Pruritus

Taylor, Roy; Taylor, Aileen; Diffey, Brian; Hindson, T.C.

doi:10.1159/000182896

Cited by 27 publications

(16 citation statements)

References 8 publications

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“…UV radiation also ameliorates pruritus in renal disease-associated itch. 98–101 Although not completely comparable, the combination of UVA and UVB appears to be better than UVA 102 or UVB311 phototherapy 103,104 in renal pruritus.…”

Section: Phototherapiesmentioning

confidence: 99%

Pruritus: Management Algorithms and Experimental Therapies

Steinhoff

Cevikbas²,

Ikoma³

et al. 2011

Seminars in Cutaneous Medicine and Surgery

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Pruritus (itch) is a major symptom in many dermatologic as well as systemic diseases and has a dramatic impact on the quality of life in these patients. The symptom of itch has to be treated on the basis of its pathophysiology and its underlying disease. In daily practice, a “quick” diagnosis of the underlying disease is often difficult, although a rapid relief of the itch is desired. We often treat patients on the basis of the symptomatology. A rational therapeutic ladder for a symptomatic therapy is useful until the final diagnosis has been confirmed. There are probably many subtypes of pruritus, just as there are many diseases that cause itch. The pathophysiology in many subtypes of pruritus is still poorly understood, hindering a rapid and targeted treatment strategy. An extensive diagnostic workup is often required to determine the final cause(s) of the itch. Thus, in daily life, physicians often start with a more or less rational therapeutic strategy to combat the debilitating itch. We present possible therapeutic ladders that form the basis for effective therapeutic itch strategies in various diseases. On the basis of our current knowledge about the different pathophysiologies of itch, on clinical trials or case reports, and our own clinical experience, we aim to present therapeutic ladders for the rapid as well as long-term management of itch. Finally, we summarize current exciting developments of experimental strategies in itch research and in clinical development for itch therapy.

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Section: Phototherapiesmentioning

confidence: 99%

Pruritus: Management Algorithms and Experimental Therapies

Steinhoff

Cevikbas²,

Ikoma³

et al. 2011

Seminars in Cutaneous Medicine and Surgery

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“…There are several treatment options such as topical capsaicin, 1 antihistamines, 2 opioid antagonists, 3 and phototherapy. [4][5][6][7] Most of the information on phototherapy for pruritus is obtained from studies on uremic pruritus. Ultraviolet radiation, especially UVB, is considered to be the treatment of choice in uremic patients.…”

Section: Introductionmentioning

confidence: 99%

Generalized pruritus treated with narrowband UVB

2007

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“…UV‐A phototherapy has also shown a beneficial effect on uremic pruritus. 33 Psoralen plus UV‐A (PUVA) photochemotherapy has also been used in treating pruritus especially in atopic dermatitis. Recently, narrow‐band UV‐A has shown promise in the treatment of pruritus in atopic dermatitis.…”

Section: Local Treatmentmentioning

confidence: 99%