A polyampholyte core-shell microgel as an environmentally sensitive drug carrier

Mackiewicz, Marcin; Dagdelen, Serife; Waleka-Bargiel, Ewelina; Karbarz, Marcin

doi:10.1016/j.arabjc.2023.105464

Arabian Journal of Chemistry

2024

DOI: 10.1016/j.arabjc.2023.105464

|View full text |Cite

A polyampholyte core-shell microgel as an environmentally sensitive drug carrier

Marcin Mackiewicz,

Serife Dagdelen,

Ewelina Waleka-Bargiel

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Article2

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Fluorinated Monodisperse Microporous Microspheres: Formation Mechanism, Assembly, and Molecular Separation

Wang,

Xu,

Qiu

et al. 2024

Chin J Polym Sci

View full text Add to dashboard Cite

Fluorinated Monodisperse Microporous Microspheres: Formation Mechanism, Assembly, and Molecular Separation

Wang,

Xu,

Qiu

et al. 2024

Chin J Polym Sci

View full text Add to dashboard Cite

Rapid Photoinduced Self-Healing, Controllable Drug Release, Skin Adhesion Ability, and Mechanical Stability of Hydrogels Incorporating Linker-Modified Gold Nanoparticles and Nanogels

Khodami,

Gharakhloo,

Dagdelen

et al. 2024

ACS Appl. Mater. Interfaces

View full text Add to dashboard Cite

Appropriately modified thermoresponsive hydrogels, such as poly(N-isopropylacrylamide) hydrogels, bring an opportunity for a variety of biomedical applications. Incorporating compounds with different properties into poly(N-isopropylacrylamide) hydrogels offers opportunities to enhance their mechanical, self-healing ability, adhesiveness, thermal responsiveness, and drug release capabilities. In this study, we investigated the influence of Au−sulfur interactions on the properties of the poly(Nisopropylacrylamide) hydrogels after introducing N,N′-bis-(acryloyl)cystine (a newly synthesized cross-linker), modified gold nanoparticles, and a p(NIPAm-BISS) nanogel into the hydrogel matrix. Our findings demonstrated that poly(Nisopropylacrylamide) hydrogels with these compounds exhibited higher mechanical strength (65% tensile stress and 25% elongation), faster thermal responsiveness, controllable self-healing [85% recovery after 2 min, using a NIR laser (800 nm, 0.75 W)], skin adhesiveness, and enhanced drug release (0.08 mg•mL −1 , a 93% improvement). These results may contribute to advancements in the design of temperature-responsive hydrogels tailored for specific biomedical needs, such as targeted drug delivery with the use of a NIR laser and tissue engineering.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

A polyampholyte core-shell microgel as an environmentally sensitive drug carrier

Cited by 2 publications

References 27 publications

Fluorinated Monodisperse Microporous Microspheres: Formation Mechanism, Assembly, and Molecular Separation

Fluorinated Monodisperse Microporous Microspheres: Formation Mechanism, Assembly, and Molecular Separation

Rapid Photoinduced Self-Healing, Controllable Drug Release, Skin Adhesion Ability, and Mechanical Stability of Hydrogels Incorporating Linker-Modified Gold Nanoparticles and Nanogels

Contact Info

Product

Resources

About