A polyethylene glycol enhanced ligation-triggered self-priming isothermal amplification for the detection of SARS-CoV-2 D614G mutation

Yu, Luxin; Tang, Zi-bin; Sun, Yuanzhong; Yi, Hai Bo; Tang, Yuebiao; Zhong, Yangqing; Dian, Dongchun; Cong, Yanguang; Wang, Houqi; Xie, Zhaoyang; He, Suhui; Chen, Zhangquan

doi:10.1016/j.talanta.2023.124711

Talanta

2023

DOI: 10.1016/j.talanta.2023.124711

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A polyethylene glycol enhanced ligation-triggered self-priming isothermal amplification for the detection of SARS-CoV-2 D614G mutation

Luxin Yu

Zi-bin Tang

Yuanzhong Sun

et al.

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Cited by 4 publications

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Intelligent point of care testing for medicine diagnosis

Gao,

2024

Interdisciplinary Medicine

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Intelligent point‐of‐care testing (iPOCT) is a rapidly advancing technology that combines molecular detection and bio‐sensing techniques to achieve instant and accurate analysis through advanced sensors and intelligent algorithms. Molecular detection technologies, such as nucleic acid isothermal amplification, biochip and microfluidics, enable rapid analysis of the chemical composition and concentration of samples, thereby determining their presence. Bio‐sensing technology utilizes the recognition properties of biomolecules in conjunction with sensors to detect specific biomolecules or biological processes. iPOCT technology holds broad prospects for application in the field of healthcare and is expected to enhance detection sensitivity, accuracy, and intelligence through further development. In this review, we delineate the developmental journey of iPOCT, followed by a discussion on the principles of molecular detection and bio‐sensing technology, as well as the design of iPOCT devices for health monitoring and disease diagnosis. Furthermore, we showcased illustrative examples of iPOCT applications in disease diagnosis, highlighting the integration of iPOCT technology with wearable devices and smartphones for attaining more precise and personalized diagnostic results.

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Intelligent point of care testing for medicine diagnosis

Gao,

2024

Interdisciplinary Medicine

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A portable all-in-one microfluidic device with real-time colorimetric LAMP for HPV16 and HPV18 DNA point-of-care testing

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Biosensors and Bioelectronics

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A novel ultrasensitive RNase H assay based on phosphorothioated-terminal hairpin formation and self-priming extension reaction

Yoon,

Lee,

Kim

et al. 2024

Biosensors and Bioelectronics

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A polyethylene glycol enhanced ligation-triggered self-priming isothermal amplification for the detection of SARS-CoV-2 D614G mutation

Cited by 4 publications

References 42 publications

Intelligent point of care testing for medicine diagnosis

Intelligent point of care testing for medicine diagnosis

A portable all-in-one microfluidic device with real-time colorimetric LAMP for HPV16 and HPV18 DNA point-of-care testing

A novel ultrasensitive RNase H assay based on phosphorothioated-terminal hairpin formation and self-priming extension reaction

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