“…Epidermal inclusion cysts of the breast typically develop during the fifth decade of life [2], and are usually located in the skin; however, they can develop in unusual locations, such as cutaneously on the nipple or areola or intra-parenchymally in the subor peri-areolar regions. Through a search of the literature, we identified a total of 21 cases where epidermal inclusion cysts developed in these unusual locations; 15 in sub- or peri-areolar region [1,3,5,12,16–19], 4 on the nipple [11,13,14,20], and 2 on the areola [10,11] (Table 1). Furthermore, we found presentations of nipple discharge in a total of 4 cases in the literature; 3 cases in sub- or peri-areolar regions [3,12,16] and 1 case on the nipple [14].…”