A population-based cohort study on sun habits and endometrial cancer

Epstein, Elisabeth; Lindqvist, Pelle G.; Geppert, Barbara; Olsson, Håkan

doi:10.1038/sj.bjc.6605149

Cited by 22 publications

(12 citation statements)

References 24 publications

(24 reference statements)

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“…However, according to recent cohort and case-control studies circulating 25(OH)D levels may play an important role in the development of pancreatic, lung, endometrial, ovarian, and other cancers [8,[42][43][44][45][46][47].…”

Section: Discussionmentioning

confidence: 98%

Obesity and increased risk of cancer: Does decrease of serum 25‐hydroxyvitamin D level with increasing body mass index explain some of the association?

Lagunova

Porojnicu

Grant

et al. 2010

Molecular Nutrition Food Res

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Low levels of vitamin D and excess body weight are both factors associated with increased risk of cancer. The increased risk seems to be proportional to the increase in BMI, and to decrease in serum 25-hydroxyvitamin D (25(OH)D) level. Our earlier investigations suggest that serum 25(OH)D levels decrease with increasing BMI. Although the connection between cancer risk, BMI and vitamin D status might be arbitrary, it has not been discussed in the literature so far. In this study, we analyze data published in current meta-analysis, prospective studies, and systematic reviews on cancer-specific risk attributed to high BMI and low vitamin D status. The contribution of low 25(OH)D levels associated with high BMI to increased cancer risk was calculated for 13 vitamin-D-sensitive cancers with a focus on colorectal and breast cancer as the most frequently studied vitamin-D-sensitive cancer types. Our study suggests that a low vitamin D status may explain at least 20% of the cancer risk attributable to high BMI. The contribution of low 25(OH)D to the increased cancer risk with increasing BMI may be different for different cancer types. Thus, we find 40% for breast cancer, and 26 and 75% for colorectal cancer in men and women, respectively.

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Section: Discussionmentioning

confidence: 98%

Obesity and increased risk of cancer: Does decrease of serum 25‐hydroxyvitamin D level with increasing body mass index explain some of the association?

Lagunova

Porojnicu

Grant

et al. 2010

Molecular Nutrition Food Res

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“…77 A study in Boston found higher bone mass density among sunbed users. 74 Two recent studies from Sweden found reduced risk of disease associated with use of sunbeds more than three times a year for endometrial cancer 78 and thrombotic events. study only claims association, not causality, and the criteria for causality do not appear to be satisfied.…”

mentioning

confidence: 99%

Critique of the International Agency for Research on Cancer meta-analyses of the association of sunbed use with risk of cutaneous malignant melanoma

Grant

2009

Dermato-Endocrinology

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“…Fish contain omega-3 fatty acids and vitamin D (30). Several previous studies showed that vitamin D reduced the risk of endometrial cancer (31,32). It has been reported that vitamin D inhibits endometrial cancer cell growth by upregulating semaphorin 3B and 3F, as well as prevents obesity-induced endometrial cancer (33,34).…”

Section: Discussionmentioning

confidence: 97%

Food Intake and the Risk of Endometrial Endometrioid Adenocarcinoma in Japanese Women

Takayama

Monma

Tsubota‐Utsugi³

et al. 2013

Nutrition and Cancer

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The present study examined the association between food intake and endometrial cancer restricted to endometrial endometrioid adenocarcinoma (EEA) using a case-control study in Japanese women. One hundred sixty-one cases and 380 controls who completed a questionnaire regarding demographic, lifestyle, and food frequency questionnaire were analyzed. Odds ratio (OR) between selected food intakes and EEA were calculated by logistic regression analysis. After adjustment putative confounding factors, the higher intakes of vegetables [odds ratio (OR) = 0.47, 95% confidence interval (CI) = 0.26-0.83], peanuts (OR = 0.48, CI = 0.27-0.86), fish (OR = 0.52, CI = 0.29-0.93), boiled egg (OR = 0.24, CI = 0.33-0.92), instant noodles (OR = 1.94, CI = 1.12-3.34), instant food items (OR = 2.21, CI = 1.31-3.74), and deep-fried foods (OR = 2.87, CI = 1.58-5.21) were associated with a risk for EEA. The inverse association with a risk of EEA was also seen in higher intakes (g/1000 kcal) for vegetables (0.45, CI = 0.25-0.81) and fish (0.53, CI = 0.30-0.94) as compare to lower intake. Higher intake of vegetables, peanuts, fish, and boiled egg was associated with a reduced risk for EEA, whereas instant noodles, instant food items, and deep-fried foods was associated with an increased risk for EAA as compared to lower levels of intake.

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A population-based cohort study on sun habits and endometrial cancer

Cited by 22 publications

References 24 publications

Obesity and increased risk of cancer: Does decrease of serum 25‐hydroxyvitamin D level with increasing body mass index explain some of the association?

Obesity and increased risk of cancer: Does decrease of serum 25‐hydroxyvitamin D level with increasing body mass index explain some of the association?

Critique of the International Agency for Research on Cancer meta-analyses of the association of sunbed use with risk of cutaneous malignant melanoma

Food Intake and the Risk of Endometrial Endometrioid Adenocarcinoma in Japanese Women

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