A population‐based study of irritable bowel syndrome in a non‐Western population

Husain, Nusrat; Chaudhry, Imran B; Jafri, Farhat; Niaz, Saad Khalid; Tomenson, Barbara; Creed, Francis

doi:10.1111/j.1365-2982.2008.01143.x

Cited by 66 publications

(64 citation statements)

References 39 publications

(72 reference statements)

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“…The marital status was not significant in the current study in accordance with previous research [17] The rate of an organic lesion on colonoscopy among patients with irritable bowel syndrome and no red flag signs was not higher as compared to healthy controls ranging from 10-40% [19,20]. By contrast: during the year following the diagnosis of irritable bowel syndrome the diagnosis of inflammatory bowel diseases was 9-16 times higher [21][22][23][24].…”

Section: Discussionsupporting

confidence: 76%

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Overlapping of Organic Disorders with Irritable Bowel Syndrome Among Teachers in Tabuk, Saudi Arabia Using Rome III Criteria

Elbadawi¹

2017

AJCEM

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Irritable bowel syndrome (IBS) is the most commonly diagnosed gastrointestinal disorder leading to losing of work days, only 15% of patients seek medical advice. In this study, we aimed to investigate IBS among teachers in Tabuk. A cross-sectional study conducted among 362 teachers in Tabuk City during the period from January 2015 to June 2015, they were selected randomly from a total number of 25 schools, participants were invited to sign a written informed consent, then responded to a structured questionnaire based on socio-demographic data, and the Rome III criteria. The research was approved by the ethical committee of the University of Tabuk. The Statistical Package for Social Sciences was used for data analysis; the chi-square was used to compare categorical data. The result shows that IBS was evident in 14.1% of teachers, IBS patients were more likely to have travelling history, and flag signs (fever, bleeding per rectum, and loss of weight) Pvalue<0.05., no differences were found between teachers with IBS and those without the disease regarding age, sex, marital status, and family history of the disease P-value >0.05. In conclusion: irritable bowel syndrome is prevalent among teachers in Tabuk, Saudi Arabia, flag signs and history of travel are commoner among those who fulfill the Rome III criteria. Physicians may need more tests to rule out organic disorders; large multicenter studies are required to rule the associations of IBS with microscopic colitis and carcinoma of the colon.

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Section: Discussionsupporting

confidence: 76%

“…The current study documented a prevalence of irritable bowel syndrome [IBS] in 14.1%, similar to studies in Riyadh Saudi Arabia [17] that reported a prevalence of 11.4% among adults. In the present study, the comment age group of IBS patients was 30-50 years old similar to the above study.…”

Section: Discussionsupporting

confidence: 70%

Overlapping of Organic Disorders with Irritable Bowel Syndrome Among Teachers in Tabuk, Saudi Arabia Using Rome III Criteria

Elbadawi¹

2017

AJCEM

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“…A survey carried out in Pakistan [7] concluded the association of irritable bowel syndrome with high income and few years of education in contradiction to the present data.…”

Section: Discussioncontrasting

confidence: 54%

Psychosocial Impact of Irritable Bowel Syndrome Among Teachers in Tabuk, Saudi Arabia

Mirghani¹,

Elbadawi²,

Alanazi³

et al. 2017

AJIM

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Abstract:In the present study, we aimed to study the psychosocial impact of irritable bowel syndrome among Saudi teachers in Tabuk. Across-sectional descriptive study was conducted among 362 teachers randomly selected from a total number of 60 schools in Tabuk City during the period January 2015 to June 2015. Participants were invited to sign a written informed consent, then responded t a structured questionnaire to collect socio-demographic factors, absence from work or sick leave due to IBS symptoms, partner employment, house type (own vs. rent), income, income adequacy, participation in care of children, continuous stress, excessive, and sleeping hours. Irritable bowel syndrome patients were more likely to be absent from work, took sick leave, and had more stress than those without the syndrome P-value < 0.05, no differences were evident between irritable bowel syndrome patients and healthy participants regarding income, house type, residency, level of exercise, smoking and sleeping hours P-value > 0.05. Irritable bowel syndrome patients were more prone to stress, absent from work, and took more sick leave than those without the syndrome. Screening for and the earlier detection of workers with irritable bowel syndrome could alleviate stress save working hours.

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“…The prevalence of IBS in Asia is reportedly 5-9% [2][3][4][5][6][7][8][9][10][11][12][13], while in Western countries it is 10-20% [14][15][16][17][18][19][20][21][22][23][24][25]. Furthermore, no female predominance was found in Asian IBS patients [2], in contrast to in Western IBS patients [22][23][24][25].…”

Section: Introductionmentioning

confidence: 99%

“…Abdominal bloating is a more common complaint than pain in Asians, and this abdominal pain is localized to the upper abdomen rather than in the lower abdomen like it is in Western patients. Moreover, alteration in bowel habits is much less prominent in Asian IBS patients than in Western patients [2][3][4][5][6][7][8][9][10][11][12][13].…”

Section: Introductionmentioning

confidence: 99%

Chromogranin A cell density in the large intestine of Asian and European patients with irritable bowel syndrome

Patcharatrakul

Hatlebakk

Hausken

et al. 2017

Scandinavian Journal of Gastroenterology

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Objective: Patients with irritable bowel syndrome (IBS) in Asia show distinctive differences from those in the western world. The gastrointestinal endocrine cells appear to play an important role in the pathophysiology of IBS. The present study aimed at studying the density of chromogranin A (CgA) cells in the large intestine of Thai and Norwegian IBS patients. Methods: Thirty Thai IBS patients and 20 control subjects, and 47 Norwegian IBS patients and 20 control subjects were included. A standard colonoscopy was performed in both the patients and controls, and biopsy samples were taken from the colon and the rectum. The biopsy samples were stained with hematoxylin-eosin and immunostained for CgA. The density of CgA cells was determined by computerized image analysis. Results: In the colon and rectum, the CgA cell densities were far higher in both IBS and healthy Thai subjects than in Norwegians. The colonic CgA cell density was lower in Norwegian IBS patients than in controls, but did not differ between Thai IBS patients and controls. In the rectum, the CgA cell densities in both Thai and Norwegian patients did not differ from those of controls. Conclusions: The higher densities of CgA cells in Thai subjects than Norwegians may be explained by a higher exposure to infections at childhood and the development of a broad immune tolerance, by differences in the intestinal microbiota, and/or differing diet habits. The normal CgA cell density in Thai IBS patients in contrast to that of Norwegians may be due to differences in pathophysiology.ARTICLE HISTORY

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A population‐based study of irritable bowel syndrome in a non‐Western population

Cited by 66 publications

References 39 publications

Overlapping of Organic Disorders with Irritable Bowel Syndrome Among Teachers in Tabuk, Saudi Arabia Using Rome III Criteria

Overlapping of Organic Disorders with Irritable Bowel Syndrome Among Teachers in Tabuk, Saudi Arabia Using Rome III Criteria

Psychosocial Impact of Irritable Bowel Syndrome Among Teachers in Tabuk, Saudi Arabia

Chromogranin A cell density in the large intestine of Asian and European patients with irritable bowel syndrome

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