A Population-Based Study of Peyronie’s Disease in Turkey: Prevalence and Related Comorbidities

Abstract

Introduction: Peyronie's disease (PD) prevalence varies between 0.39% and 20% and studies on PD prevalence are limited. Aim: This study aims to determine the prevalence of PD in males aged 30 years in Turkey and to evaluate etiological factors associated with it. Methods: The study was conducted in 12 regions of Turkey according to the Eurostat Nomenclature of Territorial Units for Statistics 1 classification and included 1,208 patients. Survey questionnaires including questions about demographic features and basic health status as well as about diagnosis and etiology of PD were put forth to the volunteers who agreed to participate in the study. Diagnosis of probable PD was established by evaluating the questionnaires. Patients with a diagnosis of congenital penile curvature were excluded from the group with PD. Chi-square test, Fisher's exact test, and Mann-Whitney U test were used. Main Outcome Measure: The primary outcome analyzed in this article was the prevalence rate of PD in Turkey and the associated comorbidities. Results: The prevalence of PD was determined as 5.3%. The rates of participants with PD were found to be the highest in the 50e59 years group (27%) and in the NorthEast Region (20%). Compared with participants without PD, participants with PD were older (median: 52 interquartile range [41e64] vs 45 [37e55]; P < .001) and the rates of smokers (73% vs 60.9%; P ¼ .036) and those having diabetes mellitus (17.5% vs 9.2%; P ¼ .045), hypertension (14.3% vs 6.9%; P ¼ .041), and heart failure were higher (7.9% vs 2.5%; P ¼ .027). Male with PD symptoms preferred their partners on top during sexual intercourse (15.2% vs 34.1%; P < .001). This is the first study to evaluate premature ejaculation prevalence and related comorbidities with face-to-face interviews. Conclusion: The prevalence of PD was 5.3% in Turkey. Besides advanced age, smoking, position of sexual intercourse, and presence of comorbidities especially diabetes mellitus, hypertension, and heart failure were the factors associated with PD prevalence.

The Use of Vacuum Devices as Adjuvant Therapy before and after Penile Curvature Surgery in Patients Affected by La Peyronie’s Disease: Results from a Comparative Study

“…Peyronie's disease (PD) represents a challenging andrological disease with an important impact on patients' quality of life [1]. The social burden of the disease is high due to its prevalence among sexually active males, ranging between 0.4 and 20%, and its chronic evolution, with a high frequency of recurrence and non-optimal efficacy in the current therapeutic strategies [2][3][4]. Moreover, its natural history is not fully understood [5].…”

Satisfaction Levels and Surgical Results of Patients Who Had Nesbit Corporoplasty Due to Penile Curvature

“…This accumulation results in fibrous tissue, eventually leading to penile deformity (1,2). The reported prevalence of PD in the general population is 0.4-20.3%, and the prevalence of definitive and probable cases of PD in Turkey is approximately 5.3% (3,4).…”

“…Surgical correction of curvature is also the only option in CPC. The surgical indication arises when the curvature of the penis prevents normal sexual intercourse or for cosmetic reasons (1,4,6).…”

“…Nesbit first described the removal of tunical ellipses opposite the point of maximum curvature with a non-elastic corporal segment in the treatment of CPC in 1965 (7). This technique was subsequently successfully used in the treatment of PD-associated penile curvature (4). The purpose of this study was to evaluate the surgical and functional efficiency of Nesbit corporoplasty, and to consider its effects on post-surgical sexual functions and postoperative complications.…”

Calcified Peyronie’s Disease Frequency on Computed Tomography

“… 3 , 4 The prevalence of PD varies between 0.4% and 23% in different case series. 5 - 7 An increase in prevalence is observed with age. 7 …”