A population-based twin study of functional somatic syndromes

Kato, Kenji; Sullivan, Patrick F.; Evengård, Birgitta; Pedersen, Nancy L.

doi:10.1017/s0033291708003784

Cited by 213 publications

(171 citation statements)

References 42 publications

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“…Twin studies have found that shared genetic factors underlie each of the six spectra (Arcos-Burgos, Velez, Solomon, & Muenke, 2012;Cosgrove et al, 2011;Hicks, Foster, Iacono, & McGue, 2013;Hicks, Krueger, Iacono, McGue, & Patrick, 2004;Kato et al, 2009;Kendler et al, 2011;Kendler et al, 2006;Kendler et al, 2003;Lichtenstein et al, 2009;Thornton, Welch, Munn-Chernoff, Lichtenstein, & Bulik, in press;Torgensen et al, 2008). Moreover, studies that span multiple spectra observed genetic dimensions that mirror the HiTOP spectra (Hink et al, 2013;Kendler et al, 2011;Kendler, Prescott, Myers, & Neale, 2003;Wolf et al, 2010).…”

Section: Research and Clinical Applications Of A Quantitative Classifmentioning

confidence: 99%

The Hierarchical Taxonomy of Psychopathology (HiTOP): A Dimensional Alternative to Traditional Nosologies

Kotov¹,

Krueger²,

Watson³

et al. 2017

Preprint

509

937

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The reliability and validity of traditional taxonomies are limited by arbitrary boundaries between psychopathology and normality, often unclear boundaries between disorders, frequent disorder co-occurrence, heterogeneity within disorders, and diagnostic instability. These taxonomies went beyond evidence available on the structure of psychopathology and were shaped by a variety of other considerations, which may explain the aforementioned shortcomings. The Hierarchical Taxonomy Of Psychopathology (HiTOP) model has emerged as a research effort to address these problems. It constructs psychopathological syndromes and their components/subtypes based on the observed covariation of symptoms, grouping related symptoms together and thus reducing heterogeneity. It also combines co-occurring syndromes into spectra, thereby mapping out comorbidity. Moreover, it characterizes these phenomena dimensionally, which addresses boundary problems and diagnostic instability. Here, we review the development of the HiTOP and the relevant evidence. The new classification already covers most forms of psychopathology. Dimensional measures have been developed to assess many of the identified components, syndromes, and spectra. Several domains of this model are ready for clinical and research applications. The HiTOP promises to improve research and clinical practice by addressing the aforementioned shortcomings of traditional nosologies. It also provides an effective way to summarize and convey information on risk factors, etiology, pathophysiology, phenomenology, illness course, and treatment response. This can greatly improve the utility of the diagnosis of mental disorders. The new classification remains a work in progress. However, it is developing rapidly and is poised to advance mental health research and care significantly as the relevant science matures.

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Section: Research and Clinical Applications Of A Quantitative Classifmentioning

confidence: 99%

The Hierarchical Taxonomy of Psychopathology (HiTOP): A Dimensional Alternative to Traditional Nosologies

Kotov¹,

Krueger²,

Watson³

et al. 2017

Preprint

509

937

View full text Add to dashboard Cite

show abstract

“…[42] In addition to FM, Irritable Bowel Syndrome, tension-type headaches, interstitial cystitis, temporomandibular joint disease (TMD), chronic fatigue syndrome, and possibly restless leg syndrome are thought to be sensory hypersensitivity conditions ( Figure 1). [43][44][45][46] These conditions often share features typical of FM including diffuse pain in multiple body regions, fatigue, sleep disorders, memory difficulties, mood disturbance, individual or familial history of chronic pain, and increased sensitivity to sensory input in the presence of an otherwise generally normal physical examination. Furthermore, sensory hypersensitivity conditions often copresent with each other suggesting a possible common pathogenesis.…”

Section: Understanding Chronic Painmentioning

confidence: 99%

Rethinking chronic pain in a primary care setting

Stanos

Brodsky

Argoff

et al. 2016

Postgraduate Medicine

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Chronic pain substantially impacts patient function and quality of life and is a burden to society at large in terms of increased health care utilization and loss of productivity. As a result, there is an increasing recognition of chronic pain as a public health crisis. However, there remains wide variability in clinical practices related to the prevention, assessment, and treatment of chronic pain. Certain fundamental aspects of chronic pain are often neglected including the contribution of the psychological, social, and contextual factors associated with chronic pain. Also commonly overlooked is the importance of understanding the likely neurobiological mechanism(s) of the presenting pain and how they can guide treatment selection. Finally, physicians may not recognize the value of using electronic medical records to systematically capture data on pain and its impact on mood, function, and sleep. Such data can be used to monitor onset and maintenance of treatments effects at the patient level and evaluate costs at the systems level. In this review we explain how these factors play a critical role in the development of a coordinated, evidence-based treatment approach tailored to meet specific needs of the patient. We also discuss some practical approaches and techniques that can be implemented by clinicians in order to enhance the assessment and management of individuals with chronic pain in primary care settings. ARTICLE HISTORY

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“…«Sentral sensitisering» (utvikling av hypersensitivitet for ulike stimuli i sentralnervesystemet), kan vaere en mekanisme ved CFS/ME (44)(45)(46) . Det trengs imidlertid flere studier før man kan konkludere sikkert.…”

Section: Utløsende Faktorerunclassified

T. Egeland og medarbeidere svarer:

Egeland¹,

Angelsen²,

Haug³

et al. 2015

Tidsskriftet

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Forfattere:Avdeling rehabilitering og sjeldne tilstander Trykk og layout: Andvord Grafisk as forord Helsedirektoratet har «følge med ansvar» for å vurdere utvikling av tjenestetilbud og om dette står i forhold til pasientgruppenes behov.På bakgrunn av erfaringer fra kontakter med pasienter, pårørende og fagpersoner er direktoratet gjort kjent med at barn, unge og voksne med CFS/ME og deres pårørende møter store utfordringer som i for liten grad ivaretas av tjenesteapparatet.Helsedirektoratets mål med denne veilederen er å bidra til faglig forsvarlighet, god kvalitet på tjenestene og tilnaermet likhet i tilbudet uansett hvor man bor som pasient med CFS/ME.Å gi helsetjenester til brukere som ikke har en klar og entydig anerkjent årsak til sin sykdom, stiller store krav til faglig kvalitet, profesjonalitet og utøvelse av tjenestetilbudet. Tidlig og riktig diagnose er viktig i et pasientforløp.Mange pasienter oppgir at de får et bedre liv når de har fått korrekt diagnose, aksepterer sykdommen og laerer seg gode mestringsstrategier for de utfordringer CFS/ME kan gi.Veilederen er utarbeidet slik at den favner et bredt felt av temaer.Veilederen bygger på dagens kunnskap og erfaring, de ordninger som er etablert i dag og gjeldende rettsregler. Det er lagt vekt på at dette først og fremst skal vaere en faglig veileder for helsepersonell.Veilederen vil bli revidert i takt med ny kunnskap.

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A population-based twin study of functional somatic syndromes

Cited by 213 publications

References 42 publications

The Hierarchical Taxonomy of Psychopathology (HiTOP): A Dimensional Alternative to Traditional Nosologies

The Hierarchical Taxonomy of Psychopathology (HiTOP): A Dimensional Alternative to Traditional Nosologies

Rethinking chronic pain in a primary care setting

T. Egeland og medarbeidere svarer:

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