The historic, cultural and Muslim brotherhood relations between Pakistan and Turkey have a long history. This imperative research tries to highlight the cultural and religious ties between the Islamabad and Istanbul. Since the creation of Pakistan, both the countries, Turkey and Pakistan, always have the historic relations particularly in the fields of cultural and religion. The primary and secondary sources have been utilized under the descriptive research method in completion of this research article. This study explores that both the countries have historic cultural as well as religious relations and always stands with each other's stances towards the culture and religion of Islam. The study further finds that Istanbul always firmly stands with the Islamabad's stances towards cultural enhancement and religious matters in the country as well as around the globe. It also suggested that cultural and religious as well as economic, military and political relations can be enhanced through more agreements, visits of high level officials, and public-to-public ties.