A Predictive Model for Clinical Asthma Exacerbations Using Albuterol eMDPI (ProAir Digihaler): A 12-Week, Open-Label Study

Safioti, Guilherme; Granovsky, Lena; Li, T.; Reich, Michael; Cohen, Shira; Hadar, Yonatan; Pleasants, Roy A.; Hill, Tanisha; DePietro, Michael

doi:10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7307

Cited by 4 publications

(4 citation statements)

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“…The device is connected via Bluetooth® technology to a companion App that provides information on inhaler use to the patient. While to date, the efficacy of Digihalers has not been evaluated; one pilot study has shown its ability to predict exacerbations [28]. Adults with exacerbation-prone asthma (n = 360) used the ProAir® Digihaler™ for 12 weeks.…”

Section: Use Of Electronic Monitoring Devices In Asthmamentioning

confidence: 99%

Wearable Technology and How This Can Be Implemented into Clinical Practice

Greiwe

Nyenhuis

2020

Curr Allergy Asthma Rep

113

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Purpose of Review Our day-today life is saturated with health data that was previously out of reach. Over the last decade, new devices and fitness technology companies are attempting to tap into this data, uncovering a treasure trove of useful information that, when applied correctly, has the potential to revolutionize the way we approach healthcare and chronic conditions like asthma, especially in the wake of the COVID-19 pandemic. Recent Findings By harnessing exciting developments in personalization, digitization, wellness, and patient engagement, care providers can improve health outcomes for our patients in a way we have never been able to do in the past. While new technologies to capture individual health metrics are everywhere, how can we use this information to make a real difference in our patients' lives? Navigating the complicated landscape of personal wearable devices, asthma inhaler sensors, and exercise apps can be daunting to even the most tech savvy physician. Summary This manuscript will give you the tools necessary to make lasting changes in your patients' lives by exposing them to a world of usable, affordable, and relatable health technology that resonates with their personal fitness and wellness goals. These tools will be even more important post-COVID-19, as the landscape of clinical outpatient care changes from mainly in-person visits to a greater reliance on telemedicine and remote monitoring. Keywords Telemedicine. Wearable devices. Personalized healthcare devices. Remote monitoring. COVID-19. Connected health This article is part of the Topical Collection on Telemedicine and Technology

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Section: Use Of Electronic Monitoring Devices In Asthmamentioning

confidence: 99%

Wearable Technology and How This Can Be Implemented into Clinical Practice

Greiwe

Nyenhuis

2020

Curr Allergy Asthma Rep

113

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“…A summary of emerging e‐Health solutions for asthma management is provided in Table 2 53,56‐62 . Overall, both digital stand‐alone and combined multicomponent interventions showed promising results on treatment adherence and clinical outcomes.…”

Section: Digital Multicomponent Interventions and Mobile‐healthmentioning

confidence: 99%

Digital health interventions in children with asthma

Ferrante

Licari

Grutta

2020

Clin Experimental Allergy

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Although healthcare providers are actively involved in offering education, information and interventions for asthmatic patients, medication and therapeutic adherence remain low in the paediatric population, with estimates suggesting that adherence rates hover below 50%. A range of available digital health interventions has been explored in paediatric asthma with promising but variable results, limiting their widespread adoption in clinical practice. They include emerging technologies that yield the advantage of tracking asthma symptoms and medications, setting drug reminders, improving inhaler technique and delivering asthma education, such as serious games (video games designed for medical‐ or health‐related purposes), electronic monitoring devices, speech recognition calls, text messaging, mobile apps and interactive websites. Some of the proposed digital interventions have used multiple components, including educational and behavioural strategies and interactions with medical professionals. Overall, the implementation of such interventions may offer the opportunity to improve adherence and asthma control. In a state of emergency as the COVID‐19 pandemic, telemedicine can also play a central role in supporting physicians in managing children with asthma. This review evaluates the published literature examining digital health interventions for paediatric asthma and explores the most relevant issues affecting their implementation in practice and the associated evidence gaps, research limitations and future research perspectives.

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“…Another study using electronic monitoring, the Propellor Health pMDI add-on device, revealed that in COPD patients a 100% increase in the use of daily rescue use was significantly associated with an acute exacerbation [76]. Preliminary results from a study investigating the real-life use of the ProAir Digihaler by patients with asthma, who had a history of acute clinical exacerbations [77] has revealed that there is an increased use of salbutamol in the days leading up to an acute exacerbation and modelling of the data identified that increased rescue use and changes in inhalation technique (PIF and Vin) were predictors of an exacerbation. There is, therefore, the potential for smart inhalers to identify an increased use of rescue medication and provide alerts so that interventions can be made to prevent an evolving acute exacerbation.…”

Section: The Potential Of Smart Inhalers To Predict Acute Exacerbationsmentioning

confidence: 99%

“…The reports highlighting the increased rescue use leading up to an acute exacerbation [75][76][77] as well as a deteriorating inhaler technique [77] suggest potential for smart inhalers to warn of an impending acute exacerbation. The role of smart inhalers to send alerts and early interventions needs extensive investigation because this could revolutionise management.…”

Section: Smart Inhalersconsiderations For the Futurementioning

confidence: 99%

Real-life inhaler adherence and technique: Time to get smarter!

Chrystyn

Audibert

Keller³

et al. 2019

Respiratory Medicine

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Smart inhalers, connected to smartphones, can provide real-life objective information about the patterns of a patient's adherence and their inhaler technique during routine use. The e-modules contain the battery and measuring sensors. Many of these are add-on modules attached externally whilst others are integrated inside the inhaler. Smart inhalers that identify a dose has either been actuated or prepared do not confirm the dose was inhaled but they can send missed dose reminders and clinical studies have highlighted their potential to improve adherence and outcomes. The e-modules that measure an inhalation profile confirm a dose has been inhaled together with providing useful information about the inhaler technique. Studies confirm that the sensors are accurate and confirm their usefulness to provide information about real-life inhaler use. Add-on e-modules are generic whereas integrated smart inhalers can be approved containing active agents and, therefore, prescribed and instructed under healthcare guidance. Real-life studies need to be carried out to demonstrate their potential to improve disease control and prevent exacerbations to justifying their increased cost.

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A Predictive Model for Clinical Asthma Exacerbations Using Albuterol eMDPI (ProAir Digihaler): A 12-Week, Open-Label Study

Cited by 4 publications

References 0 publications

Wearable Technology and How This Can Be Implemented into Clinical Practice

Wearable Technology and How This Can Be Implemented into Clinical Practice

Digital health interventions in children with asthma

Real-life inhaler adherence and technique: Time to get smarter!

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