A Prefilled Insulin Pen with a Novel Injection Mechanism and a Lower Injection Force than Other Prefilled Insulin Pens

Hemmingsen, Hans; Niemeyer, Marcus; Hansen, Marianne Rye; Bucher, Ditlef; Thomsen, Niels Bjerrum

doi:10.1089/dia.2011.0110

Cited by 20 publications

(13 citation statements)

References 29 publications

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“…Children in the MDI group tended to alternate sites less frequently than children in the CSII group and laid a higher burden on the skin and subcutaneous tissue of their administration sites by pinching and inserting needles more often. In addition, injection of insulin reaches higher forces compared to continuous subcutaneous infusion,16–17 which might lead to more direct stress on the subcutaneous tissue when using MDI. Although lipohypertrophy was associated with a longer duration of diabetes in previous studies,3, 14–15 we did not observe a statistically significant association ( p =0.08).…”

Section: Discussionmentioning

confidence: 99%

Dermatological complications of insulin therapy in children with type 1 diabetes

Munster¹,

Sande²,

Voorhoeve³

et al. 2014

European Diabetes Nursing

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Dermatological complications at insulin administration sites, like lipohypertrophy, lipoatrophy and erythema, are common in children with type 1 diabetes. These complications can be painful, disfiguring and may influence glycaemic control. Studies on epidemiology and etiology are needed before prevention or treatment is possible. The aim of this study is to determine the prevalence of common dermatological complications in children with type 1 diabetes and to assess associations between dermatological complications and possible risk factors. In this cross‐sectional study 231 children with type 1 diabetes were included. Dermatological complications were assessed and a questionnaire with possible risk factors was completed. Data were evaluated using χ2 tests. The results showed that lipohypertrophy was present in 34.8% of the children, lipoatrophy in 8.1% and erythema in 24.6%. Lipohypertrophy was associated with multiple daily injection therapy (p=0.03) and insufficiency of alternating administration sites (p<0.001). Lipoatrophy was not influenced by type of insulin therapy (p=0.44) but was found to be associated with less frequent injection site alternation in patients using multiple daily injections (p=0.01). Also, HbA1c level was positively associated with lipoatrophy (p=0.01). Erythema of the skin was more frequently diagnosed in children with continuous subcutaneous insulin pump therapy (p<0.001). A history of cutaneous infections and dry skin on exam day were independently associated with erythema at insulin administration sites (p<0.001 and 0.04, respectively). Dermatological complications are a common problem in children with type 1 diabetes making frequent examination of the skin in these children an important aspect of their medical care.

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Section: Discussionmentioning

confidence: 99%

Dermatological complications of insulin therapy in children with type 1 diabetes

Munster¹,

Sande²,

Voorhoeve³

et al. 2014

European Diabetes Nursing

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“…The torque spring is loaded during dose-setting and the spring energy is activated by depressing the push-button. Consequently, the injection force of FT is significantly lower (p50.001) than other widely used prefilled pens 25 . Insulin pens that require a relatively low injection force have previously been rated as easier and more comfortable to use by people with diabetes 26 , and this may be beneficial for patients with manual dexterity impairment or weak hand strength (such as in elderly patients) 21,[27][28][29] .…”

Section: Introductionmentioning

confidence: 90%

Usability and preference evaluation of a prefilled insulin pen with a novel injection mechanism by people with diabetes and healthcare professionals

Bailey

Thurman²,

Niemeyer

et al. 2011

Current Medical Research and Opinion

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FT was rated significantly higher (all p < 0.001) for ease of use and confidence, and was preferred over KP by people with diabetes, physicians and nurses. The features of FT may improve the insulin injection experience for a wide range of users. A limitation of the usability questionnaire employed in this study is that it did not assess the factors that influence preference. Additional analyses could be conducted using multivariate regression to help elucidate the features of FT that appeal to different users.

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“…The activation force is determined by the push-button spring. As a consequence, the injection force of FT is significantly lower than other widely used prefilled insulin pens 18,19 .…”

Section: Introductionmentioning

confidence: 96%

Healthcare professional and patient assessment of a new prefilled insulin pen versus two widely available prefilled insulin pens for ease of use, teaching and learning

Nadeau

Campos

Niemeyer

et al. 2011

Current Medical Research and Opinion

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The findings suggest that devices such as FT are easy to use and can be prescribed with relatively few training needs, which may improve ease of insulin initiation, increase pen use, and ultimately improve treatment adherence. A limitation of the usability questionnaire used in this study is that it did not assess the factors that influence preference. Further analyses could be conducted to determine the factors that appeal to different users.

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A Prefilled Insulin Pen with a Novel Injection Mechanism and a Lower Injection Force than Other Prefilled Insulin Pens

Abstract: The injection mechanism of FlexTouch means that insulin injection is driven by a torque spring and not the thumb pressure of the user. This results in a 62-82% lower injection force with FlexTouch than other prefilled insulin pens.

Cited by 20 publications

References 29 publications

Dermatological complications of insulin therapy in children with type 1 diabetes

Dermatological complications of insulin therapy in children with type 1 diabetes

Usability and preference evaluation of a prefilled insulin pen with a novel injection mechanism by people with diabetes and healthcare professionals

Healthcare professional and patient assessment of a new prefilled insulin pen versus two widely available prefilled insulin pens for ease of use, teaching and learning

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