A preliminary survey of the prevalence of allergic disorders in a questionnaire-based study in Boshroye, a rural area of Iran

Abstract

The susceptibility of 25 Stenotrophomonas maltophilia (S. maltophilia) clinical isolates to four different antimicrobials (trimethoprim/sulfomethoxazole, piperacillin/tazobactam, ceftazidime, ciprofloxacin) were investigated by disk diffusion, E-test and commercial Sensititre and PASCO broth microdilution techniques. Discrepancies between the results of broth microdilution and the other methods studied were characterized as very major, major and minor errors. Using the broth microdilution as the reference method, 24% of the isolates were found susceptible to trimethoprim/ sulfamethoxazole, 24% to ceftazidime, 0% to piperacillin/tazobactam and 12% to ciprofloxacin. Good correlation was observed between the two broth microdilution Sensititre and PASCO for all antibiotics tested. Disc diffusion and E-test generated inconsistent results for all agents except trimethoprim/sulfamethoxazole. A great genomic diversity was demonstrated within the S. maltophilia strains tested. Although our results confirm that trimethoprim-sulfamethoxazole had some in vitro activity against S. maltophilia, further clinical studies are necessary to evaluate the clinical efficacy of these compounds for the treatment of S. maltophilia infections, since no randomized controlled trials have been carried out and no correlation between the clinical response and susceptibility testing results has been reported. Furthermore, the high genomic diversity observed in the S. maltophilia strains indicates the need for careful epidemiological evaluation especially in nosocomial outbreaks.

The impact of pollen load on quality of life: a questionnaire-based study in Lithuania

“…Researchers demonstrated that hay fever symptoms have negative impact on quality of life (Linneberg et al 2002;Kiotseridis et al 2013). On the other hand, the relations of pollen and people have been predetermined by different socio-economical and geographical factors (Yamauchi et al 2009;Fereidouni et al 2010). Our study suggests that subjects have experienced the effects of allergenic pollen; however, it could be that these effects only minimally disturb their everyday and outdoor leisure activities.…”

“…Impact of pollen on the quality of life is associated with both pollen load in a territory (Fereidouni et al 2010;Velasco-Jiménez et al 2014) and lifestyle (Kiotseridis et al 2013;Lâm et al 2014). Lithuania belongs to the group of countries in which pollen of It was demonstrated in the study carried out during 2013-2014 that pollen concentrations in adjacent years can be significantly different, and prevention of diseases associated with airborne pollen becomes more difficult due to this factor.…”

Evaluation of cord blood immunoglobulin E and its association with maternal factors in a group of Iranian newborns

“…In case of allergic disorders, the prevalence of different allergic disorders in pregnant mothers is consistent with our previous surveys, and for asthma is in line with another study in Sabzevar, which is a city in the vicinity of Khorasan …”

Genotypic and Phenotypic Characterization of Stenotrophomonas maltophilia Strains from a Pediatric Tertiary Care Hospital in Serbia

“…maltophilia EUCAST set a breakpoint for TMP/SMX, even while the Clinical and Laboratory Standards Institute (CLSI) approved standards for levofloxacin, minocycline, ticarciline/calvulanate and ceftazidime. Then again, results obtained with TMP/SMX are the most reproducible, with no relation to the methods in susceptibility testing used [27]. In the Eastern and Southeast Europe, only data from Greece and Hungary are available [28, 29].…”