A pressure controlled low-level laser probe to enhance photon density in soft tissue

Numerical Modeling of Compression-Controlled Low-level Laser Probe for Increasing Photon Density in Soft Tissue

“…Therefore, the effects of skin deformation on photon density in these two regions are in opposite directions. A previous study using ex vivo porcine samples [11] presented the efficacy of the CCLLP in enhancing photon density. These results were verified by numerical simulation results ( Figure 6) which used data on in vivo changes in human skin thickness.…”

“…The peak intensities of photons in the ex vivo porcine samples [11] were compared with the simulated results. Changes in skin thickness were not obtained in the previous study because of the instability of the physical state of the ex vivo porcine skin samples.…”

“…In our previous study [11], we investigated the efficacy of CCLLP by measuring the photon density distribution in ex vivo porcine samples. In Figure 7, the photon density ratio, which is defined as the ratio of the photon density distribution between a given negative compression and no compression, was compared to the experimental data for a CCLLP with a radius of 1 cm.…”

“…In a previous study, we developed a compression-controlled low-level laser probe (CCLLP) to increase the photon density in tissues by applying negative compression [11]. Figure 1 represents the CCLLP, which consists of a vacuum hole to supply negative compression, a hollow brace for guiding and supporting the optical fiber, and an acrylic probe body to maintain the negative compression applied to the tissue.…”

“…Figure 1 represents the CCLLP, which consists of a vacuum hole to supply negative compression, a hollow brace for guiding and supporting the optical fiber, and an acrylic probe body to maintain the negative compression applied to the tissue. We experimentally validated the efficacy of the CCLLP by measuring the photon density in ex vivo porcine skin samples [11].…”