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Intensive use of pesticides in Russia puts forward the task of identifying ways to prevent their adverse effects on the health of workers. The purpose of the study is to substantiate the safety requirements when working with pesticides in agriculture from a toxicological and hygienic standpoint. An analytical study was performed. Research materials documents regulating the use of pesticides, scientific publications, data from own research. The safety of pesticides for those working with them is based on numerous toxicological and hygienic studies carried out at the stage of registration tests. According to the results of toxicological studies, including the establishment of toxicity parameters for acute inhalation, dermal and oral intake, subacute and chronic exposure, in accordance with the hygienic classification of pesticides by degree of danger, a hazard class is established, which determines the possibility, scale, technology of the use of pesticides on the territory of the Russian Federation. Particular attention is paid to the study of sensitizing effects, irritating effects on the skin and mucous membranes, as well as possible manifestations of long-term effects (teratogenic, embryotoxic, carcinogenic, mutagenic). The severity of carcinogenic and mutagenic effects determines the restriction of the use of pesticides, up to a complete ban. Hygienic regulation of the content of active substances of pesticides is carried out taking into account the hazard class and toxicity parameters. A prerequisite for the safe use of pesticides is the establishment of hygienic standards in almost all environments. The last stage of the study is an assessment of the risk to workers when using each pesticide in real conditions of agricultural production and regulation of use. Conclusion. Safety requirements for those working with pesticides when applied using various technologies in agricultural conditions are determined taking into account the hazard class of pesticides and the equipment used. The application of the method of assessing the risk of exposure to pesticides at the stage of registration tests guarantees the exclusion from circulation in Russia of drugs that pose a real danger to a working person. The minimum risk of exposure to pesticides on workers is ensured by compliance with all safety requirements and application regulations.
Intensive use of pesticides in Russia puts forward the task of identifying ways to prevent their adverse effects on the health of workers. The purpose of the study is to substantiate the safety requirements when working with pesticides in agriculture from a toxicological and hygienic standpoint. An analytical study was performed. Research materials documents regulating the use of pesticides, scientific publications, data from own research. The safety of pesticides for those working with them is based on numerous toxicological and hygienic studies carried out at the stage of registration tests. According to the results of toxicological studies, including the establishment of toxicity parameters for acute inhalation, dermal and oral intake, subacute and chronic exposure, in accordance with the hygienic classification of pesticides by degree of danger, a hazard class is established, which determines the possibility, scale, technology of the use of pesticides on the territory of the Russian Federation. Particular attention is paid to the study of sensitizing effects, irritating effects on the skin and mucous membranes, as well as possible manifestations of long-term effects (teratogenic, embryotoxic, carcinogenic, mutagenic). The severity of carcinogenic and mutagenic effects determines the restriction of the use of pesticides, up to a complete ban. Hygienic regulation of the content of active substances of pesticides is carried out taking into account the hazard class and toxicity parameters. A prerequisite for the safe use of pesticides is the establishment of hygienic standards in almost all environments. The last stage of the study is an assessment of the risk to workers when using each pesticide in real conditions of agricultural production and regulation of use. Conclusion. Safety requirements for those working with pesticides when applied using various technologies in agricultural conditions are determined taking into account the hazard class of pesticides and the equipment used. The application of the method of assessing the risk of exposure to pesticides at the stage of registration tests guarantees the exclusion from circulation in Russia of drugs that pose a real danger to a working person. The minimum risk of exposure to pesticides on workers is ensured by compliance with all safety requirements and application regulations.
Introduction. The increased interest in viticulture in Russia makes mancozeb-based fungicides in demand. Safety and health of operators during application pesticides is a major concern in agricultural activities. Materials and methods. Field studies to determine the exposure of various formulations of mancozeb in the air of the working area and on the skin of the operators during airblast spraying of orchards were carried out. Margin of safety by exposure (KBtotal) and by absorbed dose (KBabs) were conducted. Exposure assessment included the determination of its probability. Results. Wettable powders compared with water-dispersible granules show a fivefold increase in the average concentrations of mancozeb found in the air of the work area and almost a threefold increase in the skin. Exposure and absorbed dose risk rates for wettable powders are three times higher than for water-dispersible granules. For one of the drugs, the total risk was higher than the tolerable risk. The probability distribution vector of possible danger states for the operator after the sixth hour of work shows the probability of an unacceptable state as the highest. Limitations. The scopes of the study were determined by studying the behaviour of mancozeb in the formulations of the wettable powder and water-dispersible granules during airblast spraying of orchards. Conclusion. For health safety purposes, mancozeb-based preparations should be used in compliance with the regulations and safety measures. Operators, who handle and apply pesticides in orchards, should be forcing to wear protective garments and personal protective equipment. The choice of water-dispersible granules formulation is preferable. Don’t exceed the application rate and spraying time.
Introduction. Analysis and generalization of the results of scientific research of the institutions of the Federal Service for Supervision in Protection of the Rights of Consumer and Man Wellbeing (Rospotrebnadzor)institutions of a hygienic profile are extremely important in the scientific substantiation of ensuring sanitary and epidemiological well-being and managing risks to the health of the Russian population. The purpose of the study is to analyze the results, achievements and prospects of the scientific substantiation of ensuring sanitary and epidemiological well-being and managing risks to the health of the population of the Russian Federation. Materials and methods. An expert-analytical study was carried out. The analysis materials are the main results of the activities of scientific institutions of the Rospotrebnadzor of the hygienic profile in the implementation of the industry research program of Rospotrebnadzor for 2021-2025. “Scientific substantiation of the national system for ensuring sanitary and epidemiological well-being, managing health risks and improving the quality of life of the population of Russia”, as well as of the Federal Program (FP) “Clean Air” of the National Project (NP) “Ecology”, FP “Clean Water” NP “Housing and Urban Environment”, FP “Strengthening Public Health” NP “Demography”, the State Program “Provision of chemical and biological safety of the Russian Federation for the period 2021-2024”, the Federal Target Program “Ensuring nuclear and radiation safety for 2016-2020 and for the period up to 2030”. Results. Within the framework of the industry program, in the first year of its implementation, six SanPiNs, 668 hygienic standards were approved, 20 analytical reviews were prepared. 23 patents for inventions, 45 - for industrial designs, 34 - certificates for computer programs, 178 objects of intellectual activity were registered. Based on the materials of scientific research, 95 articles were published in the journals Web of Science, 328 - Scopus, 802 - RSCI. 40 monographs, books and manuals have been published. 11 PhD, 2 doctoral dissertations were defended. Limitations. The research materials are limited to the results of scientific research of the Research Institute of Hygienic Profile of Rospotrebnadzor, obtained in 2021. Conclusion. The results of the activities of the NIO Rospotrebnadzor in 2021 indicate that the set of tasks assigned to them to ensure the sanitary and epidemiological well-being of the population is being successfully implemented. Further development of interagency cooperation is required (with scientific institutions of the Russian Academy of Sciences, the Ministry of Education and Science of Russia, other ministries and departments, with medical universities); interaction with problem committees of the Scientific Council of Rospotrebnadzor, as well as further modernization and renovation of the park of laboratory and medical equipment of scientific organizations.
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