2005
DOI: 10.1002/oa.781
|View full text |Cite
|
Sign up to set email alerts
|

A probable case of gigantism in a fifth Dynasty skeleton from the Western Cemetery at Giza, Egypt

Abstract: Pituitary gigantism is a rare endocrine disorder caused by excess secretion of growth hormone during childhood. Individuals with this condition exhibit unusually tall stature due to prolonged growth as well as associated degenerative changes. Continued secretion of excess growth hormone during adulthood results in acromegaly, a related condition that results in bony overgrowth of the skull, hands and feet.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

1
26
0

Year Published

2008
2008
2018
2018

Publication Types

Select...
4
1
1

Relationship

0
6

Authors

Journals

citations
Cited by 16 publications
(27 citation statements)
references
References 29 publications
1
26
0
Order By: Relevance
“…Gigantism is a very rare disease (modern annual incidence: 3/1,000,000), rarely documented in ancient skeletal remains (Mulhern, ), so we suppose the great height of the individual we have studied must have made him a curiosity in Roman society. Unfortunately, we know nothing about the presence of giants in the Roman world and whether or not they were treated differently from others, but we know that during the Imperial Age, the members of the high society developed a pronounced taste for entertainers with evident physical malformations, such as hunchbacks and dwarfs.…”
Section: Resultsmentioning
confidence: 97%
See 1 more Smart Citation
“…Gigantism is a very rare disease (modern annual incidence: 3/1,000,000), rarely documented in ancient skeletal remains (Mulhern, ), so we suppose the great height of the individual we have studied must have made him a curiosity in Roman society. Unfortunately, we know nothing about the presence of giants in the Roman world and whether or not they were treated differently from others, but we know that during the Imperial Age, the members of the high society developed a pronounced taste for entertainers with evident physical malformations, such as hunchbacks and dwarfs.…”
Section: Resultsmentioning
confidence: 97%
“…In palaeopathological literature gigantism has been rarely documented: a Polish female skeleton probably affected by gigantism dating to 12 th –13 th centuries AD was described by Gladykowska‐Rzeczycka et al . (), and a probable case was reported in a Fifth Dynasty skeleton (2494–2345 BC) from Giza, Egypt (Mulhern, ). More common cases of acromegaly were described by Brauer (), Brothwell (), Hosovski (), Ortner (), and Charlier & Tsigonaki, .…”
Section: Introductionmentioning
confidence: 99%
“…However, body size, and stature in particular, can play an important role in assessing environmental and social factors in past populations, including general health (Steegmann and Haseley, 1988;Pietrusewsky et al, 1997, Steckel andRose, 2002), sexual dimorphism (Frayer, 1980), and class differences (Bogin and Keep, 1999). Gleser's (1952, 1958) formulae, based on long bone lengths, for US Blacks, and Robins and Shute's (1986) modified equations based on the same formulae, were previously used to estimate the stature of ancient Egyptians (Masali, 1972;Robins, 1983;Robins and Shute, 1983, 1984, 1986Zakrzewski, 2003;Mulhern, 2005). However, many authors have cautioned against using stature regression formulae derived from one population for other populations (Pearson, 1899;Stevenson, 1929;Dupertuis and Hadden, 1951;.…”
mentioning
confidence: 99%
“…Gigantism, on the other hand, is characterized by enormous long bone growth, well beyond that of the average population, leading to obvious great stature, but with the maintenance of normal body proportions (Mulhern 2005). Secondary degenerative alterations in the joints also occur.…”
Section: Endocrine Diseases In Paleopathologymentioning
confidence: 99%