2021
DOI: 10.1101/2021.01.07.21249360
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A Processed EEG based Brain Anesthetic Resistance Index Predicts Postoperative Delirium in Older Adults: A Dual Center Study

Abstract: BackgroundSome older adults show exaggerated responses to drugs that act on the brain, such as increased delirium risk in response to anticholinergic drugs. The brain’s response to anesthetic drugs is often measured clinically by processed electroencephalogram (EEG) indices. Thus, we developed a processed EEG based-measure of the brain’s neurophysiologic resistance to anesthetic dose-related changes, and hypothesized that it would predict postoperative delirium.MethodsWe defined the Duke Anesthesia Resistance … Show more

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“…On the contrary, patients who exhibit burst suppression at low anesthetic concentrations seem to have a higher incidence of POD. 31,32 Based on the available data, it remains unclear whether there is a causal relationship between intraoperative burst suppression and POD.…”
Section: Con: Eeg Should Not Be Used To Reduce Postoperative Delirium...mentioning
confidence: 99%
“…On the contrary, patients who exhibit burst suppression at low anesthetic concentrations seem to have a higher incidence of POD. 31,32 Based on the available data, it remains unclear whether there is a causal relationship between intraoperative burst suppression and POD.…”
Section: Con: Eeg Should Not Be Used To Reduce Postoperative Delirium...mentioning
confidence: 99%