A promising biomimetic surface enhances cell proliferation and adhesion ability for promoting early-stage osseointegration

Fan, Fang Yu; Wu, Chia Jen; Cho, Yung Chieh; Sugiatno, Erwan; Chou, Hsin Hua; Ou, Keng Liang; Lu, Yi Jung; Huang, Bai Hung; Ruslin, Muhammad; Huang, Maosong

doi:10.1016/j.jallcom.2020.155905

Cited by 1 publication

(2 citation statements)

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“…A surface can be functionalized to improve its physicochemical properties using the following approaches: ,,, Physical: increasing the roughness that induces the physisorption of biomolecules. Chemical: through the immobilization of proteins, peptides, calcium phosphates, drugs, etc., generating chemical bonds between the inorganic material and the biomolecule. Biological: design of bioactive or bioinspired coatings. …”

Section: Materials Biofunctionalizationmentioning

confidence: 99%

“…Since the biological response to biomaterials and devices is mostly controlled by the surface chemical arrangement, modifications can be made to improve the biointeraction of the implant without affecting the mechanical properties of the material and to increase bioresponse on the tissue−implant interface. 20,24,58 A surface can be functionalized to improve its physicochemical properties using the following approaches: 20,24,58,59 • Physical: increasing the roughness that induces the physisorption of biomolecules. • Chemical: through the immobilization of proteins, peptides, calcium phosphates, drugs, etc., generating chemical bonds between the inorganic material and the biomolecule.…”

Section: Materials Biofunctionalizationmentioning

confidence: 99%

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Microalgae Applications to Bone Repairing Processes: A Review

Payares

Púa

Pareja

et al. 2023

ACS Biomater. Sci. Eng.

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Research on regeneration and accelerated recovery processes of bone tissue has driven a growing interest in the scientific community. Implementing natural materials to reduce rejections due to biocompatibility issues is an important trend. Biofunctionalization processes have been proposed to promote osseointegration in implant materials, and those substances able to generate an adequate environment for cell proliferation are the object of several studies. Because of their high protein content and their anti-inflammatory, antibacterial, antimicrobial, and healing properties, microalgae represent a natural source of bioactive compounds, and are proposed as candidates for tissue regeneration applications. In this paper microalgae are reviewed as a source of biofunctionalized materials focused on orthopedic applications.

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