A promising trend for nano-EHS research — Integrating fate and transport analysis with safety assessment using model organisms

Lin, Sijie; Wang, Hong Tao; Tian-yu, YU

doi:10.1016/j.impact.2016.09.007

Cited by 9 publications

(3 citation statements)

References 59 publications

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“…Despite all the benefits and advantages of developing nanomaterials, there are still some major issues remained that should be addressed to avoid affecting living organisms in harmful ways [22]. Due to mesh-like structure of nanoparticles, their transportation through the extracellular Table 1 Representative engineered nanomaterials with their physicochemical properties and main applications [15].…”

Section: Using Nanomaterials For Drug Deliverymentioning

confidence: 99%

“…By classification of nanomaterial compositions, a few representative nanomaterials are displayed with respect to their innate physicochemical traits and main applications. Gold nanoparticles (Au NPs) are known as one of the most important materials with potential of being used in biomedical fields, are not listed in Table 1 as they are often used as relatively "inert" nanoparticles for the purpose of comparison in the context of environmental nanotoxicology [15].…”

Section: Introductionmentioning

confidence: 99%

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Green synthesis of silver nanoparticles toward bio and medical applications: review study

Mousavi

Hashemi

Ghasemi

et al. 2018

Artificial Cells, Nanomedicine, and Biotechnology

200

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Development of biologically inspired green synthesis of silver nanoparticles has attracted considerable worldwide attention in matter of medical science and disease treatment. Herein, the green synthesis of silver nanomaterials using organic green sources has been evaluated and discussed. These kinds of materials are widely used for treatment of antibiotic-resistant bacteria, cancer and etc due to their elegant properties compared with other chemical ways and drugs. Moreover, the outcome of green-based approaches were compared with chemical procedures and obtained data were examined via various analyses including UV-visible spectroscopy, scanning electron microscope (SEM), energy dispersive Xray spectroscopy (EDX), transmission electron microscope (TEM), atomic force microscopy (AFM) and Fourier transforms infrared spectroscopy (FT-IR). In this study, variety of green methods were investigated to present a summary of recent achievements toward highlighting biocompatible nanoparticles, all of which can reduce the toxicity of nanoparticles, make them eco-friendly, reduce their side effects and decrease the production cost. The nature of these biological organisms also affect the structure, shape, size and morphology of synthesized nanoparticles.

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Section: Using Nanomaterials For Drug Deliverymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Green synthesis of silver nanoparticles toward bio and medical applications: review study

Mousavi

Hashemi

Ghasemi

et al. 2018

Artificial Cells, Nanomedicine, and Biotechnology

200

View full text Add to dashboard Cite

show abstract

“…Standard aquatic toxicity assays using pelagic organisms (e.g., Daphnia magna , Danio rerio ) have demonstrated a range of potential environmental impacts depending on the types of engineered nanomaterials (ENMs) considered, with some being toxic at low concentrations when considered over a chronic exposure but many not toxic until very high unrealistic concentrations . However, most pristine ENMs are not stable in aqueous exposure conditions, and thus many studies on pelagic organisms largely assume exposure to the stable fraction of ENMs left behind in the water column after a majority settles out. , Testing for impacts of ENMs on benthic organisms is therefore extremely important, in certain cases perhaps more important than impacts on pelagic organisms, as many ENMs are expected to settle and concentrate to higher exposure concentrations in sediment. , Despite this, the preponderance of aquatic nanotoxicology research has focused on exposures to pelagic organisms …”

Section: Introductionmentioning

confidence: 99%

Next-Generation Complex Metal Oxide Nanomaterials Negatively Impact Growth and Development in the Benthic Invertebrate Chironomus riparius upon Settling

Niemuth

Curtis

Hang

et al. 2019

Environ. Sci. Technol.

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Most studies of nanomaterial environmental impacts have focused on relatively simple first-generation nanomaterials, including metals or metal oxides (e.g., Ag, ZnO) for which dissolution largely accounts for toxicity. Few studies have considered nanomaterials with more complex compositions, such as complex metal oxides, which represent an emerging class of next-generation nanomaterials used in commercial products at large scales. Importantly, many nanomaterials are not colloidally stable in aqueous environments and will aggregate and settle, yet most studies use pelagic rather than benthic-dwelling organisms. Here we show that exposure of the model benthic species Chironomus riparius to lithium cobalt oxide (Li x Co1–x O2, LCO) and lithium nickel manganese cobalt oxide (Li x Ni y Mn z Co1–y–z O2, NMC) at 10 and 100 mg·L–1 caused 30–60% declines in larval growth and a delay of 7–25 d in adult emergence. A correlated 41–48% decline in larval hemoglobin concentration and related gene expression changes suggest a potential adverse outcome pathway. Metal ions released from nanoparticles do not cause equivalent impacts, indicating a nanospecific effect. Nanomaterials settled within 2 days and indicate higher cumulative exposures to sediment organisms than those in the water column, making this a potentially realistic environmental exposure. Differences in toxicity between NMC and LCO indicate compositional tuning may reduce material impact.

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Biosynthesis, simulation, and characterization of Ag/AgFeO2 core–shell nanocomposites for antimicrobial applications

et al. 2021

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A promising trend for nano-EHS research — Integrating fate and transport analysis with safety assessment using model organisms

Cited by 9 publications

References 59 publications

Green synthesis of silver nanoparticles toward bio and medical applications: review study

Green synthesis of silver nanoparticles toward bio and medical applications: review study

Next-Generation Complex Metal Oxide Nanomaterials Negatively Impact Growth and Development in the Benthic Invertebrate Chironomus riparius upon Settling

Biosynthesis, simulation, and characterization of Ag/AgFeO2 core–shell nanocomposites for antimicrobial applications

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