À propos de 98 cas de dengue hospitalisés dans une clinique privée de Ouagadougou : aspects épidémiologiques, diagnostiques et évolutifs

Abstract

Extremely widespread, the dengue is a reemerging infectious disease. In Burkina Faso, dengue is a reality that was little known. The aim of this study was to study epidemiology, diagnostic and outcomes of dengue patients in Ouagadougou. A retrospective study covered a period of two years, from 1 January 2013 to 31 December 2014 in a private clinic in Ouagadougou. Patients included in the study were hospitalized for fever and painful syndrome with a positive test to the dengue non-structural antigen 1 (NS1 Ag). Ninety-eight cases of dengue on 343 suspected cases were registered. The average age of patients was 35.9 years. The sex-ratio (M/F) was 1.18. According to the professional activity, there was a predominance of civil servants (35.7%). The pain syndrome was found in 93.9% of patients. Leukopenia (73.5%), neutropenia (56.1%) and severe thrombocytopenia (57.1%) were the predominant hematological disturbances. Of the patients, 18.4% had hemorrhagic dengue and 11.2%, a dengue shock syndrome. Four patients died. The use of non-steroidal antiinflammatory drugs was associated with the severity of the infection (p=0.04). Dengue fever occurs in our context and constitutes a risk of mortality. The diagnosis of dengue should be performed systematically in front of a painful and febrile syndrome. The vector control is the best way of prevention against dengue pending the development of a vaccine.

Retrospective Evaluation of the SD BIOLINE Dengue Duo Rapid Diagnostic Test During a Dengue Epidemic in Burkina Faso

“…The average age of the patients was 29 years with a sex ratio of 0.9. These results are comparable to those of previous studies in an epidemic context [6].…”

“…In the diagnostic strategy for dengue in Burkina Faso, any patient presenting with acute fever and a negative RDT (Rapid Diagnostic Test) for malaria or a positive RDT for malaria not responding to anti-malarial treatment with signs of arboviruses is subjected to a rapid immunochromatographic test for dengue "Dengue Duo (NS1 Ag+IgM/IgG) SD (Stantard Diagnostics) Bioline". A patient who is positive for this test (positive Ig M and/or Ig G serology and/or positive NS1 antigen) should have blood drawn for confirmation by positive Ig M serology (ELISA), or increased Ig G titres or virus detection by PCR or isolation [4][5][6].…”

Video as a public health knowledge transfer tool in Burkina Faso: A mixed evaluation comparing three narrative genres

“…Dengue fever is often confused with malaria, as the symptoms of the two diseases are similar, but taking antimalarial drugs can worsen the condition of a patient with dengue fever [28]. Unfortunately, even though recent studies have reported the presence of the dengue virus in Ouagadougou, the capital of Burkina Faso [29,30], many cases of dengue continue to be misdiagnosed and improperly treated [22,31]. Very few health workers have received training on dengue fever or non-malaria febrile diseases [21,22].…”

Video As An Effective Knowledge Transfer Tool to Increase Awareness Among Health Workers and Better Manage Dengue Fever Cases.

“…Over the past two decades, the average annual number of cases of dengue haemorrhagic fever has risen dramatically [1], with a sixfold increase in incidence from 1990 to 2013 [2]. Unfortunately, many cases of dengue fever continue to be misdiagnosed and improperly treated [3]. Dengue fever is often confused with malaria because the symptoms of the two diseases are similar, sometimes leading to misdiagnosis with potentially fatal outcomes.…”