A prospective clinical study of the effects of the physical features of the appendix on perforation

Tanrıkulu, Yusuf; Yılmaz, Gökhan; Tanrıkulu, Ceren Şen; Temi, Volkan; Köktürk, Fürüzan; Cagsar, Mithat; Yalcin, Boran

doi:10.5505/tjtes.2015.77508

Cited by 7 publications

(12 citation statements)

References 21 publications

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“…However, these are not always available in health institutions or emergency units in developing country hospitals, especially in remote areas and the costs are also relatively expensive, so we can rely solely on clinical and routine laboratory examinations such as white blood count. 1,2,6 There has been a growing interest in laboratory studies used to support the diagnosis of conditions such as malignancy, heart disease and inflammation process like appendicitis, including c-reactive protein (CRP) and neutrophil-lymphocyte ratios. This examination is feasible especially in peripheral areas where radiologist support is not always available and the cost relatively cheaper.…”

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confidence: 99%

Diagnostic value of C-reactive protein and neutrophil-limphocyte ratio in perforated appendicitis at Hasan Sadikin Hospital Bandung

2017

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Background: The diagnosis of appendicitis depends on the subjective criteria of clinical examination. However, distinguishing acute perforated appendicitis (local peritonitis) and non-perforated is often difficult especially in the elderly population that usually not clinically specific unless it has developed into generalized peritonitis. Between the non-perforated acute appendicitis and perforate should be distinguished because of different surgical approaches. C-reactive protein (CRP) and neutrophil-lymphocyte ratios are known to be associated with various conditions such as malignancy, heart disease, and inflammation, including acute perforated appendicitis. This examination not only is cheaper, but also feasible and available in peripheral hospitals compared to other supports such as ultrasound or CT scan, but this examination has not been routinely used so the purpose of this study is to examine the diagnostic accuracy of both laboratory parameters so as to assist a surgeon to determine whether the case of appendicitis has been perforated or not and can provide information to patients and the families about the diseases and surgical techniques to be performed.Methods: This study used cross sectional analytic in two groups, appendicitis with and without perforation group to know the value of sensitivity, specificity, positive predictor value, negative predictor value, from CRP and RNL in both groups.Results: Of the 46 patients who met the inclusion criteria, the mean age of patients with perforated appendicitis was 33.73±17.101, male sex counted 26 patients (56.5%) and women 20 patients (43.5%). Based on ROC curve analysis, CRP = 76,65 and RNL = 8,825 were obtained, and sensitivity, specificity, positive guess, negative prediction and accuracy value for CRP were 88.0%, 71.4%, 78 %, 5%, 83.3% and 80.4%; While for RNL of 64.0%, 80.9%, 80.0%, NDN, and 71.7%.Conclusions: CRP and RNL have a strong diagnostic value and is moderately strong in cases of perforated appendicitis.

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confidence: 99%

Diagnostic value of C-reactive protein and neutrophil-limphocyte ratio in perforated appendicitis at Hasan Sadikin Hospital Bandung

2017

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“…Delay in the diagnosis and operation of appendicitis causes an increase in the perforation, morbidity, and mortality rates. [5] In the study by Barreto et al, [6] perforation was more common in males and in patients over 60 years of age; Tanrıkulu et al [7] reported that both groups were similar in terms of gender and age. In our study, the groups were similar in terms of gender, whereas patients in the perforated group were older.…”

Section: Discussionmentioning

confidence: 96%

Laparoscopic Appendectomy for Acute and Perforated Appendicitis: A Comparative Analysis

Haksal¹

2018

South Clin Ist Euras

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The purpose of this study was to compare the short-term outcomes of laparoscopically operated uncomplicated acute appendicitis and perforated appendicitis. Methods: Laparoscopically operated uncomplicated acute and perforated appendicitis were screened, retrospectively. Demographics, operative variables, and postoperative complication rates were compared between the groups. Results: Among 155 patients, acute appendicitis was found in 130 patients (77 [59.2%] male; median age, 32 [16-72]), while 25 patients (15 [60.0%] male; median age, 39 [17-84]) had perforated appendicitis. The duration of the operation and hospitalization period were 45 (20-105) minutes and 1 (1-6) day, respectively, in the acute appendicitis group, and 60 (20-155) minutes and 2 (1-16) days, respectively, in the perforated group. Total complication rates were statistically significantly higher in the perforated group. Conclusion: Laparoscopic approach can be applied in selected cases of perforated appendicitis.

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“…Tanrikulu et al (18) reported that appendiceal wall thickness, diameter and length were risk factors for perforation in their measurements of excised surgical material in patients with acute appendicitis. In our study, we did not find any relationship between length and complicated appendicitis.…”

Section: Discussionmentioning

confidence: 99%

Investigation of Laboratory Parameters That Differentiate Complicated Appendicitis from Simple Appendicitis in Adults

Dikme¹,

Dikme²

2019

Istanbul Med J

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Akut apandisit en sık görülen abdominal acillerden birisidir. Bu çalışmada basit ve komplike apandisit hastalarında preoperatif laboratuvar değerlerini incelenmeyi amaçladık. Yöntemler: Ocak-Aralık 2015 tarihleri arasında histopatolojik olarak akut apandisit tanısı konulmuş 40 yaş ve üzeri hastaların tıbbi kayıtları retrospektif olarak incelendi. Hastalar basit ve komplike olarak iki gruba ayrıldı. Beyaz kan hücresi sayımı, nötrofil sayısı ve yüzdesi, lenfosit sayısı ve yüzdesi, bazofil sayısı ve yüzdesi, trombosit sayısı, ortalama trombosit hacmi, plateletkrit, trombosit dağılım genişliği ve apandisit alt grupları arasındaki ilişki araştırıldı. Aynı zamanda nötrofil/ lenfosit oranı (NLR) ve trombosit/lenfosit oranı (PLR) da bu gruplarda analiz edildi. Bulgular: Kırk yaş üzeri 156 hasta çalışmaya dahil edildi. Hastaların 23'ü (%14,7) basit apandisitti ve tüm hastaların yaş ortalaması 50,5±8,5 yıl olarak saptandı. Erkek ve yaşlı hastalarda daha fazla komplike apandisit saptandı. Tek değişkenli analizde nötrofil yüzdesi, lenfosit sayı ve yüzdesi, lenfosit sayısı ve yüzdesi, bazofil yüzdesi, plateletkrit, NLR ve PLR değerleri gruplar arasında anlamlı farklı bulundu. Basit ve komplike apandisit verilerinin karşılaştırıldığı çok değişkenli lojistik regresyon analizinde sadece NLR değeri anlamlı bulundu. Sonuç: Kırk yaş üstü hastalarda nötrofil yüzdesi, lenfosit sayısı ve yüzdesi, bazofil yüzdesi, plateletkrit ve NLR'nin komplike apandisit ile ilişkili olduğu ancak sadece NLR'nin çok değişkenli analizde anlamlı olduğu saptandı. Buna rağmen bu parametreler başvuruda komplike apandisitin ayırt edilmesinde kullanılabilir.

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A prospective clinical study of the effects of the physical features of the appendix on perforation

Cited by 7 publications

References 21 publications

Diagnostic value of C-reactive protein and neutrophil-limphocyte ratio in perforated appendicitis at Hasan Sadikin Hospital Bandung

Diagnostic value of C-reactive protein and neutrophil-limphocyte ratio in perforated appendicitis at Hasan Sadikin Hospital Bandung

Laparoscopic Appendectomy for Acute and Perforated Appendicitis: A Comparative Analysis

Investigation of Laboratory Parameters That Differentiate Complicated Appendicitis from Simple Appendicitis in Adults

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