A prospective clinical study of interventional ultrasound sclerotherapy on women with hydrosalpinx before in vitro fertilization and embryo transfer

Letter to the Editor: Re: Comparison of IVF-ET outcomes in patients with hydrosalpinx pretreated with either sclerotherapy or laparoscopic salpingectomy

“…It has been suggested that adhesion formation could occur after transvaginal aspiration alone [3]. However, the findings described here show that all the cases undergoing ethanol injection for hydrosalpinx had severe and unfamiliar thick ovarian adhesions.…”

“…Recent studies have argued for sclerotherapy after aspirating a hydrosalpinx under ultrasound in hope of better success rate in IVF/ICSI cycles than that obtained without aspiration [2,3]. To overcome the drawback of high recurrence rate associated with ultrasound-guided transvaginal aspiration of hydrosalpinges, ethanol sclerotherapy has been introduced as a new therapeutic option.…”

Comparison of IVF-ET outcomes in patients with hydrosalpinx pretreated with either sclerotherapy or laparoscopic salpingectomy

“…However, these disadvantages may be overcome by injection of sclerosing agents into the fallopian tubes after aspiration of the hydrosalpingeal fluid [10-13]. In a study comparing sclerotherapy and untreated controls in patients diagnosed with hydrosalpinx by Jiang et al [14], the pregnancy rate was significantly higher in the study group. The author emphasized the value of sclerotherapy, hoping this might replace invasive surgeries such as salpingectomy.…”

Ultrasound sclerotherapy pretreatment could obtain a similar effect to surgical intervention on improving the outcomes of in vitro fertilization for patients with hydrosalpinx

“…Meanwhile the presence of hydrosalpinx may correlate to endometrial inflammatory response, and reduce endometrial receptivity by decreasing the expression of such molecules as HOXA10, β‐integrins, and vascular endothelial growth factor in endometrium epithelial cells, which is essential for embryo implantation . Furthermore, a decrease in endometrial and subendometrial blood flows may also be the reason for impaired implantation in patients with hydrosalpinx …”