A prospective cohort study of patients presenting to the emergency department with upper gastrointestinal bleeding

Abstract

Background: Upper gastrointestinal (UGI) bleeding is a common presentation to the Emergency Department (ED), and is associated with re-bleeding and significant mortality. Although several studies have described etiology and outcome of UGI bleeding, few have been done in the EDs. Materials and Methods: This prospective observational cohort study included all patients presenting with hematemesis or melena, between June 2016 and January 2017 to the ED. Demographic data, risk factors, endoscopy findings and prognosticating scores were noted. Patients were followed up through telephonic communication after 3 months to assess re-bleeding rate and mortality. Results: The study cohort included 210 patients with a male predominance (76.2%). The mean (SD) age was 51 (16.8) years. They presented with either hematemesis (33.8%), melena (28.6%), or both (37.6%). One third (35.7%) had variceal bleed, 21% had peptic ulcer disease (PUD), and 43.3%bled due to other etiology. UGI scopy was performed in 85.2% of patients with banding (25.1%) and sclerotherapy (14%) being the most frequently performed procedures. Endoscopic intervention was not required in 58.6%of patients. Packed red cells were transfused in 46.7% patients. The 48-h re-bleed rate among variceal bleeders was 5.3% and 11.4% among peptic ulcer bleeders. The 3-month re-bleeding rate was 42.9% and the 3-month mortality rate was 17.5% among the variceal bleeders and the same was 5.6% and 2.8%, respectively, among the peptic ulcer bleeders. The overall mortality was 12.4%. Conclusions: Variceal bleeding and PUD were the predominant causes of UGI bleeding. Overall, a quarter of our patients had a re-bleed within 3 months, with majority being variceal bleeds.

Prospective observational study on clinical and epidemiological profile of adult patients presenting to the emergency department with suspected upper gastrointestinal bleed

“…A cross-sectional study carried out by Surendran M et al at a tertiary care hospital in southern India found that males (107;77.5%) outnumbered females (31;22.5%) with an average age of 53.5 ± 13.17 years [ 9 ]. Similar results were reported by Shenoy V et al [ 10 ]. It is discernable from the above studies that UGIB is more prevalent in men than in women.…”

“…Injections of epinephrine (1:10 000 dilution), injections of sclerosants such as 100% ethanol, thermal contact devices such as bipolar electrocoagulation probes or heater probes, and clips are recommended for bleeding ulcers. Shenoy V et al observed that PRBC transfusion was done in 46.7% cases whereas 37(26.6%) cases received PRBC transfusion in our study [ 10 ]. JP Hreinsson et al found that 60% of patients presented with UGIB required blood transfusion [ 21 ].…”

Application effect of nursing model based on Rockall scoring system in emergency endoscopic treatment for patients with gastrointestinal bleeding

“…Etiological treatment and symptomatic treatment were performed simultaneously to impel the rehabilitation of patients and shorten the hospital stay [16]. Secondly, a systematic nursing model was established through the process of emergency evaluation-emergency treatment-comprehensive assessmentclinical treatment-prognostic assessment [17], the reliability of diagnosis and treatment was increased, missed diagnosis and misdiagnosis were reduced, and the danger of life in patients due to rebleeding was reduced [18].…”