A Prospective Cohort Study of Smoking in Acute Pancreatitis

Lindkvist, Björn; Appelros, Stefan; Manjer, Jonas; Berglund, Göran; Borgström, Anders

doi:10.1159/000114868

Cited by 101 publications

(101 citation statements)

References 34 publications

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“…According to a research, some medications also play a role in inducing acute pancreatitis which are classified in four different classes [5]. Smoking is also considered as a cause of acute pancreatitis depending on the age, sex, body mass index and alcohol consumption [6]. In approximately, 20% of the cases etiology remains unknown [7].…”

Section: Introductionmentioning

confidence: 99%

Complications of acute pancreatitis in tertiary care hospital

Akhter

Khan

Ahmed

et al. 2017

Int J Hepatobiliary Pancreat Dis

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Aims: The aim of this study was to determine the complications of acute pancreatitis in tertiary care hospital. Methods: Hundred patients diagnosed with acute pancreatitis were analyzed in this prospective cohort study from July 2015 to July 2016. Complications were studied. Cholelithiasis was found to be the most common cause of acute pancreatitis in our setting. Results: Acute pancreatitis is defined as reversible inflammation of pancreatic parenchyma which is characterized by the presence of interstitial edema, acute inflammatory cell infiltrate and varying degree of cellular apoptosis, necrosis and hemorrhage. Cholelithiasis and alcohol were found to be the most common causes of acute pancreatitis. Alcohol, Smoking, some medications are the major risk factors. The major complications of acute pancreatitis are pseudocyst, pleural effusion, sepsis, shock or internal bleeding, fluid collection, ascites. Conclusion: Acute pancreatitis is one of the most common gastrointestinal ailments with high morbidity and mortality worldwide and at our set up too. Like any other disease occurrence of complications may worsen the prognosis of acute pancreatitis. Acute fluid collection around pancreas came out to be the common complication.

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Section: Introductionmentioning

confidence: 99%

Complications of acute pancreatitis in tertiary care hospital

Akhter

Khan

Ahmed

et al. 2017

Int J Hepatobiliary Pancreat Dis

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“…Smoking, until recently considered only as a cofactor associated to alcohol, however some studies suggest smoking as an independent risk factor for acute and chronic pancreatitis [48].…”

Section: Other Toxinsmentioning

confidence: 99%

Etiology of acute pancreatitis

2014

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AbstractAcute pancreatitis is a common disease with a benign course in the majority of patients, but it is associated with serious morbidity, and mortality close to 20% in up to 20% of cases. The incidence of acute pancreatitis seems to be rising in western countries. About 75% of all cases are caused by gallstones or alcoholism. The relative rate of gallstones versus alcohol as etiology depends on the age and the area of enrolment. A thorough evaluation allows cause identification in another 10% of cases, leaving about 15–20% as idiopathic. The most common causes, and a growing list of less frequent and sometimes very rare and controversial etiologies, are reviewed in this article. A classification on the pathogenic mechanisms of causes of acute pancreatitis based is used in this Review. The approach, or suggested plan of investigations, to determine the etiology of acute pancreatitis, based on the most recently published Guidelines is outlined.

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“…The basic pathogenetic mechanism is considered to be the cumulative effect of successive acute insults, or the so-called necrosis-fibrosis sequence, on a background of oxidative stress [8]. In the Western world, the principal causative factor is alcohol [5], although various other effect modifiers such as smoking [9,10], diet [11,12] and genetic predisposition [13][14][15] are thought to play a part in its multifactorial aetiology. Clinical manifestations of chronic pancreatitis, which are variable in extent and time-course, are pain, malabsorption and diabetes.…”

Section: Is Acute Pancreatitis Necessarily An Acute Disease?mentioning

confidence: 99%

Acute Pancreatitis is a Chronic Disease

Turner¹

2013

Pancreat Disorders Ther

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A Prospective Cohort Study of Smoking in Acute Pancreatitis

Cited by 101 publications

References 34 publications

Complications of acute pancreatitis in tertiary care hospital

Complications of acute pancreatitis in tertiary care hospital

Etiology of acute pancreatitis

Acute Pancreatitis is a Chronic Disease

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