A Prospective Controlled Trial of Biobrane Versus Scarlet Red on Skin Graft Donor Areas

Prasad, J.K.; Feller, Irving; Thomson, Philip D.

doi:10.1097/00004630-198709000-00009

Cited by 38 publications

(12 citation statements)

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“…63 The mesh is coated with porcine type I collagen-derived peptides (dermal analogue). 65,66 Because of the large clinical experience of Biobrane since its development in 1979, Biobrane has become the standard for skin substitute coverage of thermal injuries by which other products are compared. Small pores are present to make Biobrane semipermeable to allow transudates to escape.…”

Section: Synthetic Bilayer Substitutesmentioning

confidence: 99%

Skin Substitutes and Alternatives

Shores

Gabriel

Gupta

2007

Advances in Skin &Amp; Wound Care

197

108

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Dr Shores has disclosed that he has no significant relationships with or financial interest regarding this educational activity. Dr Gabriel has disclosed that he is a member of the speaker's bureau for KCI. Dr Gupta has disclosed that he has no significant relationships with or financial interest regarding this educational activity. Drs Shores and Gupta disclosed that they plan to discuss unlabeled/investigational usage of a commercial product and will disclose this to the audience.Lippincott CME Institute, Inc. has identified and resolved all faculty conflicts of interest regarding this educational activity. PURPOSETo provide the specialist in skin and wound care with a review of skin replacement alternatives and their most common uses. TARGET AUDIENCEThis continuing education activity is intended for physicians and nurses with an interest in wound care and related disorders. OBJECTIVES After reading this article and taking this test, the reader should be able to: 1. Describe characteristics of skin and skin substitutes for grafting. 2. Identify indications for and uses of common grafting procedures and products.

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Section: Synthetic Bilayer Substitutesmentioning

confidence: 99%

Skin Substitutes and Alternatives

Shores

Gabriel

Gupta

2007

Advances in Skin &Amp; Wound Care

197

108

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“…Studies have shown that as many as half of all donor sites show signs of infection and that patients often experience pain at the donor site. 2,3 Problems with leakage of blood and fluid are also common. Infection, pain, and leakage are factors that can complicate and slow the rate of healing and result in a hypertrophic scar and either hypopigmentation or hyperpigmentation.…”

Section: Introductionmentioning

confidence: 99%

Dressing the Split-Thickness Skin Graft Donor Site

Karlsson

Lindgren

Jarnhed-Andersson

et al. 2014

Advances in Skin &Amp; Wound Care

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“…15 The infection rate with a dressing/cover can vary widely with much higher or lower infection rates than exposed wounds depending on the material used. 16,17 …”

Section: Hypertrophic Scarringmentioning

confidence: 99%

Back Grafting the Split-Thickness Skin Graft Donor Site

Goverman

Kraft

Fagan

et al. 2017

Journal of Burn Care & Research

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Split-thickness skin grafting is a useful method of wound repair in burn and reconstructive operations. However, skin grafts require a donor site injury that creates a secondary wound at risk for delayed wound healing. Though in young healthy patients such donor sites have minimal risk, patients with risk factors for delayed wound healing are more challenging. We present a method for graft donor site management that offers an alternative to healing by secondary intention for patients with higher risk of poor wound healing. In those patients considered to be at high risk for donor site healing complications, we chose to treat the donor site with a split-thickness skin graft, or “graft back” procedure. An additional graft is taken adjacent to the initial donor site, and meshed 4:1 to cover both donor sites at once. Out of the 17 patients who received this procedure, 1 patient had a complication from the procedure that did not require an operation, and all patients appear to have good functional and cosmetic outcomes. No patients had any graft loss or graft infection. Histologic analysis showed complete epithelialization of the back-grafted area. The graft back method converts an open wound to a covered wound and may result in decreased wound healing time, improved cosmetic outcomes, and fewer complications, particularly in patients where wound healing is a concern. Importantly, it seems to have minimal morbidity. More detailed prospective studies are needed to ensure no additional risk is incurred by this procedure.

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A Prospective Controlled Trial of Biobrane Versus Scarlet Red on Skin Graft Donor Areas

Cited by 38 publications

References 0 publications

Skin Substitutes and Alternatives

Skin Substitutes and Alternatives

Dressing the Split-Thickness Skin Graft Donor Site

Back Grafting the Split-Thickness Skin Graft Donor Site

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