A prospective, double-blind, randomized controlled study evaluating the effects of two new IV medications, IV acetaminophen and/or IV ibuprofen, on standard of care pain and antiemetic management in uterine fibroid embolization patients

Abstract

No. 102 Uterine artery embolization followed by elective myomectomy for the treatment of intracavitary fibroids: preliminary experience

Managing Postembolization Syndrome–Related Pain after Uterine Fibroid Embolization

“…Using IV acetaminophen and combining it with IV ibuprofen, Chaabane et al 13 showed that less opioid medication was used in comparison to the group prescribed IV ketorolac only. The authors suggest a benefit to the combination treatment, as the early data demonstrated a trend toward less opioid usage with better pain control.…”

“…23 Other common opiates used for UAE are hydromorphone, morphine, and fentanyl and/or acetaminophen with either hydrocodone or oxycodone. 3,11,[13][14][15] Saibudeen et al 24 suggested that although there were mildly better pain scores in patients receiving opioids, NSAIDs, and acetaminophen, these were not statistically significant.…”