A Prospective Evaluation of the Bedside Index for Severity in Acute Pancreatitis Score in Assessing Mortality and Intermediate Markers of Severity in Acute Pancreatitis

Singh, Vikesh K.; Wu, Bechien U.; Bollen, Thomas L.; Repas, Kathryn; Maurer, Rie; Johannes, Richard S.; Mortelé, Koenraad J.; Conwell, Darwin L.; Banks, Peter A.

doi:10.1038/ajg.2009.28

Cited by 245 publications

(190 citation statements)

References 23 publications

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“…Th e Markers of Severity in Acute Pancreatitis (MOSAP) cohort was developed at BWH, in Boston, MA ( 14,24 ). AP patients directly admitted or transferred to BWH from 2005 through 2009 were prospectively recruited.…”

Section: Study Design and Patient Populationmentioning

confidence: 99%

Admission Hematocrit and Rise in Blood Urea Nitrogen at 24 h Outperform other Laboratory Markers in Predicting Persistent Organ Failure and Pancreatic Necrosis in Acute Pancreatitis: A Post Hoc Analysis of Three Large Prospective Databases

Koutroumpakis

Bakker

et al. 2015

American Journal of Gastroenterology

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133

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Section: Study Design and Patient Populationmentioning

confidence: 99%

Admission Hematocrit and Rise in Blood Urea Nitrogen at 24 h Outperform other Laboratory Markers in Predicting Persistent Organ Failure and Pancreatic Necrosis in Acute Pancreatitis: A Post Hoc Analysis of Three Large Prospective Databases

Koutroumpakis

Bakker

et al. 2015

American Journal of Gastroenterology

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133

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“…Regarding severe AP, the Atlanta classification establishes the Ranson 8 or APACHE II 9 criteria for characterization of severity. These methods, however, have limitations reported by other studies [10][11][12][13][14][15] . In 2008, the review of the Atlanta classifivcation 16 defined the severity of acute pancreatitis, at least in the first week, is based on clinical components and suggested that the persistence of a systemic inflammatory response syndrome and / or organ failure should be considered.…”

Section: Introduction Introduction Introduction Introduction Introducmentioning

confidence: 55%

“…We observed seven patients with organ failure among the dead in a week of hospitalization. However, despite its use established in the Atlanta classification 4 , it is a method that requires 48 hours to complete the evaluation, hampering the analysis within the first 24 hours, which is important in view of the prevention of possible adverse events [10][11][12] .…”

Section: Discussion Discussion Discussion Discussion Discussionmentioning

confidence: 99%

Severity assessment of acute pancreatitis: applying Marshall scoring system

Carioca

Jozala

et al. 2015

Rev. Col. Bras. Cir.

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Objective: To analyze the effectiveness of the Marshall scoring system to evaluate the severity of acute pancreatitis (AP). Methods : We performed a prospective, observational study in 39 patients with AP evaluated by the Marshall scoring system and the Ranson criteria (admission and 48 hours). We assessed the progression of the disease for seven days and compared the data of the two criteria. Results : Seven patients died during the observation period and one died afterwards. All deaths had shown failure of at least one system by the Marshall method. Conclusion : The Marshall scoring system may be used as an effective and simplified application method to assess the severity of acute pancreatitis.

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“…The Ranson and modified Glasgow score contain data not routinely collected at the time of hospitalization. 1,2 Both require 48h to complete, missing a potentially valuable early therapeutic window. [1][2][3] The APACHE II was originally developed as an intensive care instrument and requires the collection of a large number of parameters, some of which may not be relevant to prognosis in acute pancreatitis.…”

mentioning

confidence: 99%

“…1,2 Both require 48h to complete, missing a potentially valuable early therapeutic window. [1][2][3] The APACHE II was originally developed as an intensive care instrument and requires the collection of a large number of parameters, some of which may not be relevant to prognosis in acute pancreatitis. 4,5 There is a need for a simple and clinically oriented severity scoring system that can predict severity of acute pancreatitis within 24h of presentation.…”

mentioning

confidence: 99%

Prospective evaluation of the BISAP score and its correlation with Marshall score in predicting severity of organ failure in acute pancreatitis

et al. 2017

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Background: The bedside index for severity in acute pancreatitis (BISAP), a newer prognostic scoring system, has been proposed as a simple and clinically oriented severity scoring system for early identification of patients with acute pancreatitis. This study evaluates the efficacy of BISAP score to predict the severity of organ failure in patients of acute pancretitis and its correlation with Marshall score.Methods: The clinical, laboratory and radiological data for all patients admitted with a diagnosis of acute pancreatitis conducted at tertiary hospital of Armed Forces over a two-year period, was prospectively collected for this study. BISAP score was calculated within 24hrs of presentation. Markers of severity were the development of organ failure and presence of pancreatic necrosis. Outcome at 28 days (viz. recovery, organ failure and mortality) was studied for each patient. BISAP score computed at 24h was correlated with the above and its efficacy to predict the severity of organ failure in Acute Pancreatitis, was assessed.Results: Out of 50 patients in the study group, 41 were male and 9 were female with the mean (±SD) age 43.74±16.85 years. Majority of the study population had alcohol (56%) as the etiology followed by gall stones (28%). Outcome assessed at 28 days revealed recovery of 54%, complication of 36% and mortality of 10% of study population. BISAP score computed within 24 hours of admission of 2 or more significantly predicted the severity and complication with P value <0.001. Statistically significant trends of increasing severity and organ failure (P<0.001) with increasing BISAP was observed.Conclusions: BISAP score is a reliable means of predicting the severity and organ failure and stratifying patients with Acute Pancreatitis within 24 hours of admission. The statistically significant incidence of increasing severity and mortality with increasing BISAP score will help us to risk stratify the patients within 24 hours of admission and help improve clinical care and facilitate necessary interventions as early as possible.

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A Prospective Evaluation of the Bedside Index for Severity in Acute Pancreatitis Score in Assessing Mortality and Intermediate Markers of Severity in Acute Pancreatitis

Cited by 245 publications

References 23 publications

Admission Hematocrit and Rise in Blood Urea Nitrogen at 24 h Outperform other Laboratory Markers in Predicting Persistent Organ Failure and Pancreatic Necrosis in Acute Pancreatitis: A Post Hoc Analysis of Three Large Prospective Databases

Admission Hematocrit and Rise in Blood Urea Nitrogen at 24 h Outperform other Laboratory Markers in Predicting Persistent Organ Failure and Pancreatic Necrosis in Acute Pancreatitis: A Post Hoc Analysis of Three Large Prospective Databases

Severity assessment of acute pancreatitis: applying Marshall scoring system

Prospective evaluation of the BISAP score and its correlation with Marshall score in predicting severity of organ failure in acute pancreatitis

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