A Prospective Multicenter Study on the Prevalence and Symptoms of Erosive Reflux Esophagitis in Secondary and Tertiary Hospitals in Korea

Hwang, Jin Ki; Kim, Juhyung; Hong, Seung Goun; Jung, Sung Joo; Joo, Moon Kyung; Lee, Beom Jae; Park, Jong Jae; Kim, Jae Seon; Bak, Young Tae

doi:10.4166/kjg.2009.53.5.283

Cited by 20 publications

(12 citation statements)

References 27 publications

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“…It is clear that endoscopy is the only method of investigation to make a diagnosis of erosive esophagitis and grading its severity. According to a recent report, prevalence of erosive esophagitis in secondary and tertiary hospitals in Korea was 11.8% 20. In the present study, prevalence of erosive esophagitis by EGD in type II DM patients was 18.9%.…”

Section: Discussionsupporting

confidence: 49%

Gastroesophageal Reflux Disease in Type II Diabetes Mellitus With or Without Peripheral Neuropathy

Lee¹,

Keum²,

Chun³

et al. 2011

J Neurogastroenterol Motil

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Background/AimsPatients with type II diabetes mellitus (DM) were known to have higher prevalence of gastroesophageal reflux disease (GERD). Recent studies have shown that neuropathy has positive role on the development of GERD in type II DM, although its pathogenesis has not been fully understood yet. The aim of this study was to investigate whether neuropathy really contribute to the development of GERD and typical GERD symptoms in patients with type II DM in Korea.MethodsOne hundred and nineteen patients with type II DM who had given informed consents were enrolled. All patients underwent electromyography to check the presence of peripheral neuropathy, face-to-face interview to evaluate their typical GERD symptoms and esophagogastroduodenoscopy to look for the presence of erosive esophagitis. Ninety-five patients were finally included for this study and they were divided according to the presence or absence of the peripheral neuropathy.ResultsThe mean age of 95 patients was 59.3 ± 9.1 years and the mean disease duration of DM was 9.3 ± 5.9 years. Typical GERD symptoms were similarly found in both groups with and without peripheral neuropathy (23.6% vs 22.8%, P = 0.921). Erosive esophagitis was more prevalent in patients with neuropathy than in those without neuropathy (31.5% vs 10.5%, P = 0.022).ConclusionsIn patients with type II DM, peripheral neuropathy is an independent risk factor for the erosive esophagitis. However, peripheral neuropathy did not contribute to the presence of the typical GERD symptoms.

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Section: Discussionsupporting

confidence: 49%

Gastroesophageal Reflux Disease in Type II Diabetes Mellitus With or Without Peripheral Neuropathy

Lee¹,

Keum²,

Chun³

et al. 2011

J Neurogastroenterol Motil

Self Cite

View full text Add to dashboard Cite

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“…The term heartburn is less well understood in Asia. A previous Korean study has reported that the most common presenting symptom in patients with reflux esophagitis is epigastric pain or discomfort and that acid regurgitation is more prevalent than heartburn [44].…”

Section: Discussionmentioning

confidence: 99%

Determinants of symptoms in gastroesophageal reflux disease

Choi

Jung

Song

et al. 2013

European Journal of Gastroenterology & Hepatology

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“…The severities of reflux related symptoms (heartburn, acid regurgitation, chest discomfort, chest pain, hoarseness, globus sensation, cough, epigastric pain, epigastric soreness and dyspepsia)10 were recorded by 10 cm VAS running from 0 (no symptom) to 10 (maximal symptom expression).…”

Section: Methodsmentioning

confidence: 99%

Relationship Between Gastroesophageal Reflux Symptoms and Dietary Factors in Korea

Song¹,

Chung²,

Lee³

et al. 2011

J Neurogastroenterol Motil

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Background/AimsThe incidence of gastroesophageal reflux disease (GERD) is increasing in Korea. The aim of this study was to evaluate the relationship between GERD symptoms and dietary factors in Korea.MethodsFrom January 2007 to April 2008, 162 subjects were enrolled (81 in GERD group and 81 in control group). They were asked to complete the questionnaires about GERD symptoms and dietary habits. The symptom severity score was recorded by visual analogue scale.ResultsSubjects with overweight or obesity had an increased risk for GERD (OR, 2.52; 95% CI, 1.18-5.39). Irregular dietary intake was one of the risk factors for GERD (OR, 2.33; 95% CI, 1.11-4.89). Acid regurgitation was the most suffering (2.85 ± 2.95 by visual analogue scale) and frequent reflux-related symptom (57.5%) in GERD. Noodles (OR, 1.22; 95% CI, 1.12-1.34), spicy foods (OR, 1.09; 95% CI, 1.02-1.16), fatty meals (OR, 1.20; 95% CI, 1.09-1.33), sweets (OR, 1.42; 95% CI, 1.00-2.02), alcohol (OR, 1.16; 95% CI, 1.03-1.31), breads (OR, 1.17; 95% CI, 1.01-1.34), carbonated drinks (OR, 1.69; 95% CI, 1.04-2.74) and caffeinated drinks (OR,1.41; 95% CI, 1.15-1.73) were associated with symptom aggravation in GERD. Among the investigated noodles, ramen (instant noodle) caused reflux-related symptoms most frequently (52.4%).ConclusionsWe found that noodles, spicy foods, fatty meals, sweets, alcohol, breads, carbonated drinks and caffeinated drinks were associated with reflux-related symptoms.

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A Prospective Multicenter Study on the Prevalence and Symptoms of Erosive Reflux Esophagitis in Secondary and Tertiary Hospitals in Korea

Cited by 20 publications

References 27 publications

Gastroesophageal Reflux Disease in Type II Diabetes Mellitus With or Without Peripheral Neuropathy

Gastroesophageal Reflux Disease in Type II Diabetes Mellitus With or Without Peripheral Neuropathy

Determinants of symptoms in gastroesophageal reflux disease

Relationship Between Gastroesophageal Reflux Symptoms and Dietary Factors in Korea

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