A Prospective Program to Reduce the Clinical Incidence of Clostridium difficile Colitis Infection after Cystectomy

Calaway, Adam; Jacob, Joseph M.; Tong, Yan; Shumaker, Luke; Kitley, Weston; Boris, Ronald S.; Cary, Clint; Kaimakliotis, Hristos Z.; Masterson, Timothy A.; Bihrle, Richard; Koch, Michaël

doi:10.1016/j.juro.2018.09.030

Cited by 4 publications

(2 citation statements)

References 18 publications

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“…Therefore, pre-operative screening can provide appropriate preventive measures. A study at Indiana University revealed that, for patients who tested positive for Clostridium difficile pre-surgery, immediate treatment with protective isolation and metronidazole reduced the rate of symptomatic infection post-surgery by about half ( 27 ).…”

Section: Discussionmentioning

confidence: 99%

3D laparoscopic treatment of bladder cancer with pelvic multi-organ invasion: a case report and literature review

Chen,

Deng,

Sun

et al. 2023

Front. Oncol.

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IntroductionRadical cystectomy with dissection of pelvic lymph nodes and urethral diversion is the standard surgical treatment for muscle-invasive non-metastatic bladder cancer. In rare cases where patients with bladder cancer without distant metastasis have pelvic multi-organ invasion, the cancer compresses or invades the ureter and, in severe cases, leads to bilateral upper urinary tract obstruction and renal damage. The treatment recommended by guidelines often cannot improve the patients’ clinical symptoms immediately, and patients cannot complete the treatment owing to severe side effects, resulting in poor survival benefits.Case presentationA 69-year-old woman with facial edema was treated at the First Affiliated Hospital of Jinan University. The serum creatinine and potassium values were 1244 umol/L and 5.86 mmol/L, respectively. Pelvic magnetic resonance and abdominal computed tomography revealed that the bladder tumor had infiltrated the uterus, anterior vaginal wall, rectum, right ureter, right fallopian tube, and right ovary and metastasized to multiple pelvic lymph nodes. Tumor invasion of the right ureter resulted in severe hydronephrosis of the right kidney and loss of function and obstructive symptoms in the left kidney. Four days later, the patient’s creatinine level decreased to 98 u mol/L, the general condition significantly improved, and the patient and family members strongly desired surgical treatment of the tumor. Through a comprehensive preoperative discussion, possible intraoperative and postoperative complications were evaluated. Right nephrectomy, right ureterectomy, total pelvic organ resection, extended pelvic lymph node dissection, and bowel and urinary diversion were conducted under 3D laparoscopy-assisted treatment. The patient was followed-up for 1.5 years and showed good tumor control, self-care, and mental status.ConclusionMinimally invasive surgery is a curative option for patients with bladder cancer with pelvic multi-organ invasion without distant metastasis. Surgeons should strictly control the indications for surgery and warn patients about the occurrence of related post-surgical complications.

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Section: Discussionmentioning

confidence: 99%

3D laparoscopic treatment of bladder cancer with pelvic multi-organ invasion: a case report and literature review

Chen,

Deng,

Sun

et al. 2023

Front. Oncol.

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“…In a provocative study Calaway et al (page 342) from Indianapolis, Indiana performed prospective screening for CD before surgery, and used contact isolation and prophylactic metronidazole in those who screened positive. 9 The incidence of clinical CD infection declined from 9.4% to 5.5%. Further studies are needed to learn whether CD prophylactic screening and treatment should be incorporated into enhanced recovery after surgery protocols.…”

Section: Screening Program To Reduce Clostridium Difficile Colitis Infection After Cystectomymentioning

confidence: 97%

This Month in Adult Urology

Smith¹

2019

Journal of Urology

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Some months back I wrote in this column that readers who thought there were too many prostate cancer papers in The Journal of UrologyÒ should be delighted since there were only a few such papers in that issue. I also warned that was likely not to persist and this issue shows that prophecy to be true as more than two-thirds of the articles in this issue are on prostate cancer.Neither of these situations (too many or too few prostate cancer articles) was planned. There is no target threshold for papers on a particular topic and it is the policy of The Journal to consider and publish manuscripts that reach across the entire domain of urology. Indeed, in this issue, in addition to the Pediatric Urology Section and Urological Survey Section, the review article and topics in the JU Forum feature section are not about prostate cancer. However, although the fact is that prostate cancer is the most frequent topic reported, each submission is judged based on its individual merits. So, the content of The Journal may vary but the commitment to publishing the most clinically relevant and important new advances throughout the specialty will not change.

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Management of Common Complications After Radical Cystectomy, Lymph Node Dissection, and Urinary Diversion

2021

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A Prospective Program to Reduce the Clinical Incidence of Clostridium difficile Colitis Infection after Cystectomy

Abstract: Clostridium difficile screening prior to cystectomy is associated with a significant decrease in rates of clinically symptomatic infections postoperatively. These results should be confirmed in a randomized controlled trial.

Cited by 4 publications

References 18 publications

3D laparoscopic treatment of bladder cancer with pelvic multi-organ invasion: a case report and literature review

3D laparoscopic treatment of bladder cancer with pelvic multi-organ invasion: a case report and literature review

This Month in Adult Urology

Management of Common Complications After Radical Cystectomy, Lymph Node Dissection, and Urinary Diversion

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