A prospective randomised clinical and histological study of superficial burn wound healing with honey and silver sulfadiazine

Subrahmanyam, M

doi:10.1016/s0305-4179(97)00113-7

Cited by 272 publications

(172 citation statements)

References 10 publications

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“…Several authors have reported that honey enhances wound healing rate, compared to other conventional or topical applications in a variety of clinical conditions, namely, burns, chronic wounds, infected surgical wounds, and pressure ulcers [8][9][10][11][12][13][14].…”

Section: Discussionmentioning

confidence: 99%

A Prospective Randomized Study to Compare the Effectiveness of Honey Dressing vs. Povidone Iodine Dressing in Chronic Wound Healing

et al. 2012

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Section: Discussionmentioning

confidence: 99%

A Prospective Randomized Study to Compare the Effectiveness of Honey Dressing vs. Povidone Iodine Dressing in Chronic Wound Healing

et al. 2012

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“…Besides the anti-infectious activity of honey, a lot of studies highlighted its anti-inflammatory, anti-edematous and anti-exudative activities, as shown by assessment of wound evolution [30,[43][44][45][46][47][48], biochemical tests of indicators of inflammation (decreased malondialdehyde and lipid peroxide levels) [49][50][51] and histopathology exams (decrease of inflammatory cells) [43].…”

Section: The Anti-inflammatory Activity Of Honeymentioning

confidence: 99%

“…Moreover, honey has a wound debriding action, evidenced in clinical trials [43][44][45][46][47][48][69][70][71][72][73]. Honey activates plasminogen and increases plasmin activity, which lyses fibrin attaching slough, by suppression of the macrophage plasminogen activation inhibitor.…”

Section: Debriding Activity Of Honeymentioning

confidence: 99%

“…Furthermore, honey has nutritional action in the wound, indirectly through osmotic drainage, which brings nutrients necessary for wound healing from interstitial fluid, but also directly through input of easily metabolisable carbohydrate, amino acids, vitamins and minerals [23,43,74]. Studies have evidenced that wounds heal faster if they are applied a mixture of nutrients [75][76][77].…”

Section: The Nutritional Activity Of Honeymentioning

confidence: 99%

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Honey, Food and Medicine: Scientific Rationale and Practical Efficiency in External Administration of Medicinal Honey for Wound Healing

Zbuchea¹

2017

JAST-B

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Except for its benefits as food and medicine, honey has been used since ancient times as an external remedy in wound care, and has been the subject of numerous studies and research, that reveal its complex favorable action for wound healing. Based on scientific research and clinical studies published in literature, this work presents these various properties and therapeutic activities of honey dressings. Next, actions and clinical effects of L-Mesitran range of dressings, based on medicinal honey and authorized European Union (EU) and Food and Drug Administration (FDA), have been highlighted in a case series of patients in the Department of Plastic Surgery, Emergency District Hospital of Ploiesti, Romania, by monitoring the clinical local evolution of burns and other wounds. L-Mesitran range of products is based on the combination of medicinal honey and other ingredients, such as hypoallergenic medicinal lanolin, vitamins C and E. These sterilized preparations were applied for various skin lesions after wound cleansing, and exerted a favorable action on healing of burns and other wounds, sometimes in combination with surgical treatment, being applied in these cases before or after surgery. Further clinical studies are needed to establish the best indications, methods and forms of administration for each type of wounds, as well as the selection over other types of dressings.

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“…The clinical applications of honey, particularly in the treatment of wounds, ulcers and burns are quite striking. It has been reported that honey promotes wound epithelization (Efem, 1993;Bergman, 1983;Efem, 1988;Subrahmanyam, 1988;Suguna, 1993), reduce inflammation (Subrahmanyam, 1998), edema (Efem, 1993;Efem, 1988;Gunther, 2010) and exudation (Efem, 1993;Efem, 1988), and accelerates synthesis of collagen and increase DNA content of the granulation tissue (Suguna, 1993;Lu et al, 2005;Ozlugedik, 2006;Koo et al, 2002;Park et al, 1998).…”

Section: Introductionmentioning

confidence: 99%

Medical Dressing Treated with Honey/Chitosan Microencapsules

Elnagar

Nagi

El-Gamal

2012

IJC

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Wound normally left to dry and dressing keeps infections out as well as reducing the trauma. Advanced technology is used to reduce pain and fast healing with avoiding the deformation of the injured skin. In this work previously UV/ozone irradiated medical dressing samples were treated by honey capsulated in chitosan. Treatment conditions were optimized with respect to weight; air-permeability; whiteness; yellowness and antibacterial. All treated samples showed good antimicrobial performance with sufficient air permeability and weight. The sticky nature of the honey was avoided by formation of microencapsules. Treated gauze samples showed good performance for injured rates with no inflammation.

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A prospective randomised clinical and histological study of superficial burn wound healing with honey and silver sulfadiazine

Cited by 272 publications

References 10 publications

A Prospective Randomized Study to Compare the Effectiveness of Honey Dressing vs. Povidone Iodine Dressing in Chronic Wound Healing

A Prospective Randomized Study to Compare the Effectiveness of Honey Dressing vs. Povidone Iodine Dressing in Chronic Wound Healing

Honey, Food and Medicine: Scientific Rationale and Practical Efficiency in External Administration of Medicinal Honey for Wound Healing

Medical Dressing Treated with Honey/Chitosan Microencapsules

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