A prospective randomized comparison of extensive prostate biopsy to standard biopsy with assessment of diagnostic yield, biopsy pain and morbidity

Sur, Roger L.; Borboroglu, Prodromos G.; Roberts, James L.; Amling, Christopher L.

doi:10.1038/sj.pcan.4500713

Cited by 11 publications

(9 citation statements)

References 23 publications

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“…For TRUS-guided biopsies, the relation between prostate volume and the number of biopsy cores to pain during biopsy is inconsistent. Some authors have observed that larger prostate glands [25,26], younger age [25,26], or higher number of biopsy cores [27] are associated with increased pain, while others have not [28][29][30]. In our study, we did not observe a correlation between these parameters and the MPP score in any group.…”

Section: Discussioncontrasting

confidence: 76%

Comparison of patient comfort between MR-guided in-bore and MRI/ultrasound fusion-guided prostate biopsies within a prospective randomized trial

et al. 2015

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Section: Discussioncontrasting

confidence: 76%

Comparison of patient comfort between MR-guided in-bore and MRI/ultrasound fusion-guided prostate biopsies within a prospective randomized trial

et al. 2015

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“…The early attempts to mitigate pain evaluated several methods that included general anesthesia, intrarectal local anaesthetic application (18), pudendal and caudal nerve blocks, rofecoxib (19), intravenous propofol (20), nitrous oxide inhalation (21), intravenous conscious sedation (fentanyl and midazolam) (22), intrarectal glyceryl trinitrate (23, 24), intrarectal diclofenac (25), and 40% dimethyl sulfoxide. Some of these methods were of doubtful efficacy (26), while for some methods like intravenous propofol and general anesthesia, a trained team and operating theater-like set-up were needed.…”

Section: Introductionmentioning

confidence: 99%

Pain during Transrectal Ultrasound-Guided Prostate Biopsy and the Role of Periprostatic Nerve Block: What Radiologists Should Know

Nazir

2014

Korean J Radiol

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Early prostate cancers are best detected with transrectal ultrasound (TRUS)-guided core biopsy of the prostate. Due to increased longevity and improved prostate cancer screening, more men are now subjected to TRUS-guided biopsy. To improve the detection rate of early prostate cancer, the current trend is to increase the number of cores obtained. The significant pain associated with the biopsy procedure is usually neglected in clinical practice. Although it is currently underutilized, the periprostatic nerve block is an effective technique to mitigate pain associated with prostate biopsy. This article reviews contemporary issues pertaining to pain during prostate biopsy and discusses the practical aspects of periprostatic nerve block.

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“…Conversely, in our study, prostate volume did not effect VAS scores in both groups. In the prostate biopsy, various other analgesia methods were investigated using intravenous conscious sedation (fentanyl and midazolam), nitrous oxide inhalation, oral analgesia (paracetamol/codeine), intrarectal diclofenac and 40% dimethyl sulfoxide [22,23]. Obek et al showed a meaningful reduced level of pain with local lidocaine gel application before PPNB whereas tradamol and periprostatic blockage had similar effects [24].…”

Section: Discussionmentioning

confidence: 99%

Untitled

2019

J Clin Anal Med

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Aim: In this study, we aimed to compare the efficiency of two different local anesthetic techniques in transrectal ultrasound (TRUS) guided prostate biopsy. Material and Method: The medical records of 798 patients who underwent 12 core transrectal ultrasound guided prostate biopsy were evaluated retrospectively. The patients were divided into 2 groups to receive two different kinds of anesthesia during the procedure as follows: Group 1, rectal application of 2% lidocaine gel and Group 2 periprostatic nerve block. The perception of pain during the insertion of the probe and during the biopsy procedure was scored for each group separately by using a visual analog scale (VAS). Results: The mean age, mean total PSA level and mean prostate volume of the patients in Group 1 were 67.67 ± 8.91 years, 12.57 ± 17.67 ng/ml and 51.41 ± 22.62 ml respectively. The mean age, mean total PSA level and mean prostate volume of the patients in Group 2 were 64.64 ± 7.63 years, 13 ± 18.02 ng/ml and 53.44 ± 44.01 ml respectively. The mean VAS scores of Group 1 and Group 2 during probe insertion were 4,87 ± 1,14 and 5,19 ± 1,16 respectively (p<0.001). The mean VAS scores during biopsy were 3,56 ± 1,43 for Group 1 and 2,5 ± 0,91 for Group 2. The difference between these scores was statistically significant (p<0.001). Discussion: Using of lidocaine gel for analgesia in TRUS-guided prostate biopsy significantly decreases the perception of pain experienced during the probe insertion procedure. On the other hand, PPNB is more effective than the using of lidocaine gel in pain control when the level of pain experienced during the biopsy is examined. Analgesia is substantially ensured by using PPNB, but analgesia combined with topical anesthetic agents could provide a more comfortable biopsy procedure.

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A prospective randomized comparison of extensive prostate biopsy to standard biopsy with assessment of diagnostic yield, biopsy pain and morbidity

Cited by 11 publications

References 23 publications

Comparison of patient comfort between MR-guided in-bore and MRI/ultrasound fusion-guided prostate biopsies within a prospective randomized trial

Comparison of patient comfort between MR-guided in-bore and MRI/ultrasound fusion-guided prostate biopsies within a prospective randomized trial

Pain during Transrectal Ultrasound-Guided Prostate Biopsy and the Role of Periprostatic Nerve Block: What Radiologists Should Know

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