A prospective randomized controlled trial of laparoscopic repair versus open repair for perforated peptic ulcers

Laparoscopic versus open repair of perforated peptic ulcer: A retrospective cohort study

“…The conversion rate to open procedures in the present study was 15%—a rate at the lower end of the spectrum of conversion rates in recent studies, which range from 1.7% to 67% . In the present study, one reason for conversion was diagnostic uncertainty, which adds additional weight to the utility of the laparoscopic approach.…”

“…Comparisons between laparoscopic repair and open repair have been inconclusive, with no clearly preferable choice apparent in recent meta‐analyses and randomized controlled trials . It has been established that peptic ulcer disease is affected by wide geographical differences , and most randomized studies included in meta‐analysis have been based in Europe and China . There is, therefore, a paucity of Australian data in this area.…”

Curative effect of laparoscopic surgery on acute gastric perforation

“…When the stomach or duodenum perforates, digestive juice gets into the enterocoelia via the perforation site leading to diffuse peritonitis. The development of the disease is characterized by acute onset, great damage and poor prognosis [1,2], and if it is not repaired in time, it will further result in septicopyemia and systemic inflammatory response syndrome. The severe one will develop multiple organ dysfunction syndrome and even die [3].…”

Surgical treatment of perforated gastroduodenal peptic ulcers: comparison between open and laparoscopic approach

“…1 In despite of this, the incidence of perforated PUD has increased because of the wider use of nonsteroidal antiinflammatory drugs (NSAIDs). 2 In Mexico the prevalence of H. pylori remains high, with prevalence in the open population of 66% and more than 80% in people older than 26 years.…”

“…Laparotomy has long been the standard treatment of perforated peptic ulcers (PPU). 1 After the first description of the procedure by Mouret et al and Nathanson et al in the nineties, a number of studies have demonstrated that laparoscopic repair is feasible and safe and even better than the open approach. [4][5][6][7][8] The aim of this study is to compare the surgical outcomes of patients with perforated gastric or duodenal peptic ulcers treated either open or laparoscopic in our institution.…”