A Prospective Randomized Double-Blinded Study of the Effect of Intravenous Fluid Therapy on Adverse Outcomes on Outpatient Surgery

Coagulation, inflammatory, and stress responses in a randomized comparison of open and laparoscopic repair of recurrent inguinal hernia

“…All patients were infused with isotonic saline 20 ml/kg during surgery in accordance with recent expert recommendations [10] and a randomized study showing that crystalloid infusion of this magnitude improves patientsÕ well-being after ambulatory surgery [24].…”

The relationship between arginine vasopressin levels and hyponatremia following a percutaneous renal biopsy in children receiving hypotonic or isotonic intravenous fluids

“…This study was of short duration, namely, 5 h, making it difficult to generalize as to what the outcome would have been had the study had been carried out to 12-24 h. In addition, a more liberal definition of hyponatremia (serum sodium <137 mEq/L) was used, based on the reference range for the laboratory rather then the standard definition of <135 mEq/L. One could also argue that there was no absolute indication for intravenous fluids in this group of patients and that they may have fared equally well had no perioperative fluid been administered, but there is data to suggest that supplemental intravenous fluids do decrease post-operative nausea or vomiting in outpatient surgery [27]. The amount of fluid given in the study could also be considered excessive, with intravenous fluid rates exceeding by twofold the standard maintenance in some patients.…”

Präoperative Nüchternzeiten

“…Ein Verbesserung des Patientenkomforts wurde auch durch intra-bzw. postoperative intravenöse Flüssigkeitssubstitution erzielt [13,15,35,39]. Mithilfe perioperativer Glukose-und Insulininfusion kann zwar eine normale Insulinsensitivität nach der Operation aufrechterhalten werden [28].…”