“…However, PDT was associated with a reduced incidence of wound infection (odds ratio = 0.28, 95% confidence interval, 0.16 to 0.49, P < .0005) when compared to surgical tracheostomy. 22 Other outcome measures such as costs, procedure duration, and use of minimal resources (such as materials or staff) are still controversial 2,6,19 due to methodological flaws such as selection bias (observed in nonrandomized studies 3,4,6 ) or comparisons between heterogeneous groups (such as bedside PDT versus open tracheostomy performed either bedside or in the OR 2,3,11,12 ). The advantages of a bedside procedure are demonstrated in one of the cited meta-analyses 22 ; reduced bleeding (odds ratio = 0.29, 95% confidence interval, 0.12 to 0.75, P = .01) and mortality (odds ratio = 0.71, 95% confidence interval, 0.50 to 1.0, P = .05) were observed for PDT when compared to surgical tracheostomy performed in the OR (no difference was found when compared to OBT).…”