A Prospective, Randomized Study of Preoperative Autologous Donation for Hip Replacement Surgery

Schultz, W.; Weinstein, James Neil; Weinstein, Stuart L.; Smith, Brian G.

doi:10.2106/00004623-200208000-00003

Cited by 130 publications

(82 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In line with our results, in a randomised study by Billote et al, 8 the patients undergoing unilateral primary total hip replacement, who had donated autologous blood at least 2 weeks prior to surgery, showed lower Hb levels both at the time of admission and in the recovery room than those who had not donated autologous blood. Except one of the hip replacement patients, all the others who were autotransfused received their blood transfusion only postoperatively.…”

Section: Collection Of Autologous Blood From Bm Donors T Parkkali Et Alsupporting

confidence: 92%

Collection of autologous blood for bone marrow donation: how useful is it?

Parkkali

Juvonen

Volin

et al. 2005

Bone Marrow Transplant

View full text Add to dashboard Cite

Summary:The hospital charts of 495 adult bone marrow (BM) donors to adult patients were reviewed to determine how necessary it is to collect autologous blood for marrow donation. An autologous transfusion was given to 79% of the donors. The median total volume of marrow harvested was 900 ml (range 450-1350 ml). The median number of nucleated cells harvested was 3.2 Â 10 8 /kg patient weight (range 0.9-7.4 Â 10 8 /kg patient weight). On the morning following the harvest, the median haemoglobin (Hb) concentrations were

show abstract

Section: Collection Of Autologous Blood From Bm Donors T Parkkali Et Alsupporting

confidence: 92%

Collection of autologous blood for bone marrow donation: how useful is it?

Parkkali

Juvonen

Volin

et al. 2005

Bone Marrow Transplant

View full text Add to dashboard Cite

show abstract

“…The use of autologous blood transfusion for elective orthopaedic surgery is decreasing, despite an overall upward trend in transfusion rates driven by an increase in allogeneic transfusions [7,45]. The decrease in this practice may be attributable to growing concerns regarding its cost-effectiveness and utility in patients without anemia [4,6,18,20], the possibility of iatrogenic anemia leading to increased overall transfusion rates [9,12,19], and some reports suggesting no differences regarding postoperative mortality and infection compared with allogeneic transfusions [9,30]. It therefore is possible that patients of higher socioeconomic status are asking for preoperative donation of blood to their own detriment, and, paradoxically, disadvantaged populations may not be receiving substandard care.…”

Section: Discussionmentioning

confidence: 99%

Minorities Are Less Likely to Receive Autologous Blood Transfusion for Major Elective Orthopaedic Surgery

Menendez

Ring

2014

Clinical Orthopaedics &Amp; Related Research

View full text Add to dashboard Cite

Background Surgeons commonly arrange for patients to perform autologous blood donation before elective orthopaedic surgery. Understanding sociodemographic patterns of use of autologous blood transfusion can help improve quality of care and cost containment. Questions/purposes We sought to determine whether there were (1) racial disparities, (2) insurance-based disparities, or (3) income-based disparities in autologous blood use. Additionally, we evaluated the combined effect of (4) race and insurance and (5) race and income on autologous blood use, and we compared ratios of autologous with allogeneic blood use.

show abstract

“…Potential complications of autologous blood include bacterial contamination, febrile non-hemolytic transfusion reactions, and technical or clerical errors with the handling of samples. The benefit of PABD for non-anaemic patients undergoing primary unilateral total hip replacement has been questioned in the literature [16,20,21]. In light of the fact that the cost of donating, storing, and transfusing autologous blood is similar to that of allogeneic blood, the cost-efficacy of PABD is primarily a function of the number of units discarded [22].…”

Section: Discussionmentioning

confidence: 99%

Targeted pre-operative autologous blood donation: a prospective study of two thousand and three hundred and fifty total hip arthroplasties

Monsef

Figgie

Mayman

et al. 2014

International Orthopaedics (SICOT)

View full text Add to dashboard Cite

Purpose Pre-operative donation of autologous blood has been widely used in elective joint replacement procedures to avoid the risks of allogeneic blood transfusions. However, the high percentage of wasted autologous blood questions the general efficacy of pre-operative autologous blood donation (PABD) for all patients undergoing hip replacement. This study prospectively investigates the impact of a targeted pre-operative autologous blood donation protocol for anaemic patients on allogeneic and overall transfusion rates in 2,350 unilateral primary total hip arthroplasty procedures. Methods Patients with pre-operative haemoglobin less than 12.5 g/dL were advised to donate one unit of autologous blood seven to 15 days prior to the date of surgery. The targeted protocol was followed by 2,251 patients: 280 out of 367 anaemic patients donated while 1,971 out of 1,983 nonanaemic patients did not donate. Results Results showed a significantly lower rate of allogeneic transfusion for anaemic patients who predonated than anaemic patients who did not (13 % vs. 37 % respectively, p<0.001). Overall transfusion rates for patients who followed the protocol (n=2,251) were found to be 0.17 units/patient compared to previously reported numbers of 0.75 units/patient when routine donation was used. Among the 2,251 patients who followed the protocol, only 140 patients (6 %) had their autologous blood wasted, in contrast to values reported in the literature ranging from 14 % up to 50 %. Conclusions Targeted PABD reduces the need for allogeneic blood transfusion in anaemic patients and significantly reduces the overall number of transfusions compared to routine pre-operative autologous donation.

show abstract

A Prospective, Randomized Study of Preoperative Autologous Donation for Hip Replacement Surgery

Cited by 130 publications

References 46 publications

Collection of autologous blood for bone marrow donation: how useful is it?

Collection of autologous blood for bone marrow donation: how useful is it?

Minorities Are Less Likely to Receive Autologous Blood Transfusion for Major Elective Orthopaedic Surgery

Targeted pre-operative autologous blood donation: a prospective study of two thousand and three hundred and fifty total hip arthroplasties

Contact Info

Product

Resources

About