A Prospective Series of Patients with Chronic Achilles Tendinopathy Treated with Autologous-conditioned Plasma Injections Combined with Exercise and Therapeutic Ultrasonography

Deans, Victoria M.; Miller, Anthony; Ramos, James

doi:10.1053/j.jfas.2012.06.009

Cited by 51 publications

(27 citation statements)

References 31 publications

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“…The use of ACP has only been addressed by Deans et al and concerned therapy of chronic tendinpoathy of the Achilles tendon [22]. The author tested 26 patients with tendinopathy of the Achilles tendon which had lasted for at least six months.…”

Section: Discussionmentioning

confidence: 99%

A randomized study of autologous conditioned plasma and steroid injections in the treatment of lateral epicondylitis

Lebiedziński

Synder

Buchcic

et al. 2015

International Orthopaedics (SICOT)

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Purpose Chronic tendinopathy of lateral epicondyle of the humerus, commonly known as Btennis elbow^is one of the most frequent tendinopathies caused by recurrent overload of the muscle origins. The aim of the study was to assess the effectiveness of treating lateral epicondylitis (LE) with autologous conditioned plasma (ACP) and betamethasone injections, and to compare these methods over the course of a one year follow-up. Methods Patients were randomly placed into one of into two groups: 53 were treated with ACP, and 46 with 1 ml betamethasone injections and 2 ml of 1 % lignocaine. Both those groups were comparable in terms of initial DASH score. Results After six weeks and six months, the mean DASH score was significantly better in the betamethasone group, but was better in ACP group after one year. Full recovery (patients with no symptoms) at all time points was more common in the betamethasone group. A comparison of grouped DASH scores revealed more very good and good results in the ACP group after one year. More patients had pain symptoms related to injection in the ACP group than the betamethasone group. Conclusions ACP therapy of LE allows better results to be obtained at 12 months. Betamethasone injections give more rapid improvement, but the therapeutic effect is longer lasting in the ACP group.

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Section: Discussionmentioning

confidence: 99%

A randomized study of autologous conditioned plasma and steroid injections in the treatment of lateral epicondylitis

Lebiedziński

Synder

Buchcic

et al. 2015

International Orthopaedics (SICOT)

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“…Deans et al [30] showed an increased in the quality of life and functional outcomes in patients treated with PRP, but de Vos [31] in 2010 and de Jong et al [32] in 2011 reported no significant difference in improvement using the functional scores at 6, 12, and 24 weeks and at 1 year when PRP was compared to the ECC and placebo groups. Among patients who were treated with L-PRP, 91.6-93.0% [33,34] were satisfied after treatment and 89% returned to sport [33] with no Achilles tendon rupture [34] (Table 1).…”

Section: Platelet Rich Plasma and Leukocyte-and Platelet-rich Plasmamentioning

confidence: 99%

Conservative Treatment of Chronic Achilles Tendinopathy: A Systematic Review

Pavone

Vescio

Mobilia

et al. 2019

JFMK

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Achilles tendinopathy is a common musculoskeletal disorder. Athletes, runners and jumpers, and the sedentary are frequently affected. Numerous are the therapeutic choices to manage these kinds of disorders. The aim of this review is to analyze the available literature to document the up-to-date evidence on conservative management of Achilles tendinopathy. A systematic review of two medical electronic databases was performed by three independent authors, using the following inclusion criteria: conservative treatment consisted of pharmacologic, physical therapy without operative treatment, with more of 6 months symptoms and a minimum average of 6-months follow-up. Studies of any level of evidence, reporting clinical results, and dealing with Achilles tendinopathy and conservative treatment were searched for. A total of n = 1228 articles were found. At the end of the first screening, following the previously described selection criteria, we selected n = 94 articles eligible for full-text reading. Ultimately, after full-text reading and a reference list check, we selected n = 29 articles. Achilles tendinopathy is a frequent musculoskeletal disorder and several conservative treatments have been proposed, but no therapy is universally accepted, except for eccentric exercise training, which is the gold standard and a commonly used protocol.

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“…Several small studies have shown postinjection improvements in pain, tendon structure, return to activities, and quality of life. 100,[102][103][104][105][106][107] In addition to decreased pain, Ferrero and colleagues 100 found statistically significant structural changes in Achilles tendons 6 months after PRP combined with dry needling treatment including decreased tendon size, decreased echogenicity, and increased power Doppler signal indicating an induced vascular response. Other studies have supported these results, with subjective and objective positive benefits as much as 18 months after PRP.…”

Section: Achilles Tendinopathymentioning

confidence: 99%