A prospective study comparing different iodine concentrations for triphasic multidetector row CT of the upper abdomen

Sandstede, J.; Werner, Alexander; Kaupert, Christine; Roth, Anne; Jenett, M.; Harz, Cornelia; Hahn, Dietbert

doi:10.1016/j.ejrad.2006.05.012

Cited by 19 publications

(26 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As mentioned above, several studies comparing the influence of different iodine concentrations of contrast medium on vascular and parenchymal enhancement have already been performed comparing different injection protocols for various body regions [10,[14][15][16][17][18][19][20][21][22][23]. Most of these studies set their focus on parenchymal contrast Obscured anatomic detail, enhancement not sufficient for diagnosis Blurred Extensive Fig.…”

Section: Discussionmentioning

confidence: 99%

“…Intravascular or parenchymal enhancement is clearly affected by all major parameters of the injection protocol applied, including the total volume of contrast material, the iodine concentration, the injection rate and accordingly the duration of injection [1][2][3][5][6][7][8][9][10][11][12][13]. Different contrast material volumes or flow rates also contrast media with different iodine concentrations have been compared [10,[14][15][16][17][18][19][20][21][22][23]. Some studies reported that intravenous administration of contrast media with high iodine concentration yields higher intravascular and parenchymal attenuation than contrast media with a lower iodine concentration [16,17,19,21,22].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Which Iodine concentration in chest CT? – A prospective study in 300 patients

et al. 2008

View full text Add to dashboard Cite

In computed tomography (CT) several contrast media with different iodine concentrations are available. The aim of this study is to prospectively compare contrast media with iodine concentrations of 300, 370 and 400 mg iodine/ml for chest- CT. 300 consecutive patients were prospectively enrolled, under a waiver of the local ethics committee. The first (second, third) 100 patients, received contrast medium with 300 (370, 400) mg iodine/ml. Injection protocols were adapted for an identical iodine delivery rate (1.3 mg/s) and total iodine load (33 g) for all three groups. Standardized MDCT of the chest (16 x 0.75 mm, 120 kVp, 100 mAseff.) was performed. Intravascular attenuation values were measured in the pulmonary trunk and the ascending aorta; subjective image quality was rated on a 3-point-scale. Discomfort during and after injection was evaluated. There were no statistically significant differences in contrast enhancement comparing the three contrast media at the pulmonary trunk (p = 0.3198) and at the ascending aorta (p = 0.0840). Image quality (p = 0.0176) and discomfort during injection (p = 0.7034) were comparable for all groups. General discomfort after injection of contrast media with 300 mg iodine/ml was statistically significant higher compared to 370 mg iodine/ml (p = 0.00019). Given identical iodine delivery rates of 1.3 g/s and iodine loads of 33 g, contrast media with concentrations of 300, 370 and 400 mg iodine/ml do not result in different intravascular enhancement in chest-CT.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Which Iodine concentration in chest CT? – A prospective study in 300 patients

et al. 2008

View full text Add to dashboard Cite

show abstract

“…It has been shown that contrast enhancement of the abdomen is directly affected by the total iodine dose and the iodine delivery rate [1][2][3][4][5][6][7][8][9][10][11][12]. Comparison of the influence of different iodine concentrations of contrast media on vessel and parenchyma enhancement was the subject of several previous studies [5,9,[13][14][15][16][17][18][19][20]. Yet, all of these studies evaluated the effect of contrast media containing different iodine concentrations only inter-individually, comparing groups of different patients [15][16][17][18][19].…”

Section: Introductionmentioning

confidence: 98%

“…Comparison of the influence of different iodine concentrations of contrast media on vessel and parenchyma enhancement was the subject of several previous studies [5,9,[13][14][15][16][17][18][19][20]. Yet, all of these studies evaluated the effect of contrast media containing different iodine concentrations only inter-individually, comparing groups of different patients [15][16][17][18][19]. Contrast enhancement, however, is affected by individual factors like patient age, body-mass index [BMI=weight in kg divided by the square of height (m)], cardiac output or circulation times; with non-uniform distribution of these factors in an interindividual comparison the results of contrast enhancement measurement can easily be biased [21].…”

Section: Introductionmentioning

confidence: 99%

Contrast enhancement in multidetector-row computed tomography (MDCT) of the abdomen: intraindividual comparison of contrast media containing 300 mg versus 370 mg iodine per ml

et al. 2008

View full text Add to dashboard Cite

The purpose of this study was to intraindividually evaluate the difference in intraluminal vessel and parenchyma contrast enhancement of two different iodine concentrations in multidetector-row computed tomography (MDCT) of the abdomen. Eighty-three patients underwent baseline and follow-up MDCT-scanning (Somatom Sensation 16; Siemens, Forchheim, Germany) of the abdomen using contrast media containing 370 mg iodine/ml (protocol A; Ultravist 370, Bayer Schering Pharma, Berlin, Germany) and 300 mg iodine/ml (protocol B; Ultravist 300). The total iodine load (37 g iodine) and the iodine delivery rate (1.29 g iodine/s) were identical for both protocols. Contrast enhancement in the portal venous phase was measured in the abdominal aorta, inferior vena cava, portal vein, liver, spleen, pancreas and kidney. Mean attenuation values were compared using paired t-test. Intraindividual comparison revealed no statistically significant differences of the mean attenuation values between protocols A and B for all anatomic sites: abdominal aorta, inferior vena cava, portal vein, liver, spleen, pancreas and kidney (all P > 0.05). Given an injection protocol with constant total iodine load and constant iodine delivery rate, the iodine concentration of contrast media does not significantly influence abdominal contrast enhancement in the portal venous phase.

show abstract

“…It has become critical for planning further treatment or evaluation. There have been several articles comparing the qualities of images derived from different iodine concentrations in the upper abdomen or renal arteries using 240, 300, or 370 mgI/ mL (18,19). However, no reports have characterized small renal lesions using these different iodine concentrations.…”

mentioning

confidence: 99%

Analysis of the Effects of Different Iodine Concentrations on the Characterization of Small Renal Lesions Detected by Multidetector Computed Tomography Scan: A Pilot Study

Lee

Kim

Cho

et al. 2017

J Korean Soc Radiol

View full text Add to dashboard Cite

Multidetector computed tomography (MDCT) of the abdominal solid organs, including the liver and kidney, is an essential imaging modality of routine clinical practice for the diagnosis, treatment planning, and follow-up of many diseases. The diagnostic accuracy of CT examination is highly dependent on the imaging protocols and, in particular, on contrast media (CM) Purpose: Our objective was to compare the effects of different iodine concentrations on characterizing small renal lesions. Materials and Methods: Thirty-eight patients were enrolled in this study. All patients underwent an initial CT scan using 370 mgI/mL iodinated contrast media. Patients were then randomized into two groups for a follow-up CT. Group A (n = 19) received 250 mgI/mL iodinated contrast media, and group B (n = 19) received 300 mgI/mL contrast media. The mean Hounsfield units (HU values) of small renal lesions with a maximum size of less than 2 cm were calculated. Signal to noise ratios (SNR values) were likewise evaluated. Three uroradiologists assessed the lesion's conspicuity and the diagnostic influence of the artifact's proximity to the adjacent renal parenchyma. Results: In group A, there were significant differences between the HU values of renal lesions and those of the adjacent renal parenchyma between the initial and follow-up CT. Conversely, in group B, there was no significant difference. Moreover, SNR values showed no statistically significant difference between both groups. Regarding lesion conspicuity, only one reader identified a significant difference (p = 0.032) in group A; whereas in group B, there was no statistical difference. The artifact's proximity to the adjacent renal parenchyma did not appear to have any diagnostic influence on differentiating the two (p < 0.05). Conclusion:In evaluating small renal lesions, 300 mgI/mL instead of 370 mgI/mL contrast media can be used; however, it is important to note that the use of 250 mgI/ mL contrast media may reveal different results from that of 370 mgI/mL contrast media. Index terms

show abstract

A prospective study comparing different iodine concentrations for triphasic multidetector row CT of the upper abdomen

Cited by 19 publications

References 19 publications

Which Iodine concentration in chest CT? – A prospective study in 300 patients

Which Iodine concentration in chest CT? – A prospective study in 300 patients

Contrast enhancement in multidetector-row computed tomography (MDCT) of the abdomen: intraindividual comparison of contrast media containing 300 mg versus 370 mg iodine per ml

Analysis of the Effects of Different Iodine Concentrations on the Characterization of Small Renal Lesions Detected by Multidetector Computed Tomography Scan: A Pilot Study

Contact Info

Product

Resources

About